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research Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype

24 citations , May 2019 in “PLOS genetics”

This study reports that compound heterozygous loss-of-function mutations in the HEPHL1 gene in a child were associated with abnormal hair and cognitive issues, linking altered ferroxidase activity to hair disorders.

research Biallelic Variants in Lanosterol Synthase (LSS) Cause Palmoplantar Keratoderma-Congenital Alopecia Syndrome Type 2

8 citations , April 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study identified biallelic variants in the LSS gene as a possible genetic cause of palmoplantar keratoderma-congenital alopecia syndrome type 2, highlighting the role of cholesterol synthesis in skin cornification.

Case Report: A Chinese Family of Woodhouse-Sakati Syndrome With Diabetes Mellitus, With a Novel Biallelic Deletion Mutation of the DCAF17 Gene

research Case Report: A Chinese Family of Woodhouse-Sakati Syndrome With Diabetes Mellitus, With a Novel Biallelic Deletion Mutation of the DCAF17 Gene

3 citations , December 2021 in “Frontiers in endocrinology”

In this study, a novel DCAF17 gene mutation was identified in a Chinese family, suggesting a potential role in pancreatic β cell dysfunction and diabetes development in Woodhouse-Sakati syndrome.

research Bias Assessment and Data Drift Detection in Medical Image Analysis: A Survey

1 citations , September 2024 in “arXiv (Cornell University)”

This study reviews methods to ensure the reliability of machine learning models in medical imaging, focusing on bias detection, data drift assessment, and accuracy estimation without ground truth labels to enhance integration into clinical settings.

research Bias in Hair Cortisol Measures for Psychological Stress: Self vs. Professional Collection

January 2026 in “Psychoneuroendocrinology”

Self-collected hair samples can measure stress but may need adjustments for accuracy.

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Community Join

5 / 343 results

community Summary of Procapil video by Haircafe

2 upvotes 1 year ago

Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

community About those dutasteride studies 😒

22 upvotes 1 year ago

Dutasteride studies for hair loss are often sponsored by GlaxoSmithKline, raising concerns about potential bias. Despite this, some users report positive results with dutasteride and oral minoxidil, while others remain skeptical of industry-funded research.

community Why is nobody talking about the new study results for Pyrilutamide??

53 upvotes 1 year ago

Pyrilutamide shows promising hair growth results, but skepticism exists due to potential biases and lack of blinding in the study. Concerns about side effects and legitimacy of the product persist, with comparisons to finasteride and discussions on post-finasteride syndrome.

community Publication concludes finasteride is a associated with a 60% risk of persistent sexual dysfunction.

345 upvotes 6 months ago

Finasteride is not linked to a 60% risk of persistent sexual dysfunction; this figure applies only to those already experiencing sexual issues. Most users do not have side effects, and the study's methodology is criticized for selection bias.

community Topical dutasteride significantly outperforms oral finasteride

in Research/Science 65 upvotes 11 months ago

Topical dutasteride 0.05% is reported to outperform oral finasteride with minimal side effects, but concerns about study bias exist due to company funding. Some users report mixed results with topical dutasteride, noting issues with skin penetration and systemic absorption.

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Learn

2 / 801 results

learn Hair Transplant

How much does a DHI hair transplant cost? DHI hair transplant costs range from $1,500 to $40,000 depending on various factors.
How much does a hair transplant cost? Hair transplant costs typically range from $1,000 to $25,000 depending on various factors.

learn Scalp Micropigmentation

Will scalp micropigmentation work with gray hair? Scalp micropigmentation works well with gray hair using customized gray-scale pigments.

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Experts

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Clinics

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