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This case report describes a 28-year-old man with widespread pigmented basal cell carcinomas and recurrent infections that were challenging to control, associated with nevus comedonicus and a rudimentary toe.

This article reviews the case of a patient diagnosed with basal cell nevus syndrome and reports no new research findings.

This review discusses the role of Hedgehog signaling in basal cell carcinoma development and highlights genetic mouse models and potential targeted therapies, but reports no new clinical results.

This study suggests that NBCCS and BFHS may be the same genetic condition, which could help improve identification and management of misdiagnosed cases with specific surveillance strategies.

This review reports that sonidegib and vismodegib, two Hedgehog inhibitors used for treating advanced basal cell carcinoma, have similar efficacy and safety profiles, but differ in pharmacokinetics, with sonidegib achieving peak concentration more rapidly and reaching steady state later than vismodegib.