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the stimulant you know and love can be used topically to stimulate hair
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glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin
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5 / 1000+ resultsresearch Acetyl-CoA Synthesis in the Skin Is a Key Determinant of Systemic Lipid Homeostasis
This study investigates the role of ATP-citrate lyase (ACLY) in lipid metabolism by using inducible whole-body Acly-knockout mice. The findings reveal that ACLY is essential for skin homeostasis, as its deficiency leads to upregulation of acetyl-CoA synthetase ACSS2. When both Acly and Acss2 are deleted from the skin, it results in significant skin abnormalities, affecting lipid production in the epidermis and sebaceous glands differently. The epidermis experiences a depletion of barrier lipids, while sebaceous glands increase sebum production, partly due to circulating fatty acids and adipose lipolysis. Dietary fat supplementation enhances sebum production and partially mitigates lipoatrophy and skin abnormalities. The study underscores the importance of cytosolic acetyl-CoA synthesis in skin barrier integrity and positions the skin as a crucial organ in systemic lipid regulation.
research Glycerol Regulates Stratum Corneum Hydration in Sebaceous Gland Deficient (Asebia) Mice
Glycerol is essential for skin hydration in mice without sebaceous glands.
research The Stratum Corneum Barrier: Impaired Function in Relation to Associated Lipids and Proteins
The skin's outer layer relies on lipids and proteins to protect against damage.
research Acyl-CoA Binding Protein and Epidermal Barrier Function
ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.
research Stratum Corneum Dysfunction in Dandruff
Improving skin barrier and using antifungal treatments can help manage dandruff.
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5 / 251 resultscommunity I started rapidly diffuse thinning at 22. I'm 42 now and have as much hair as I did at 16. AMA
Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.
community Oral Fin+Min: Digital microscope scalp review - Day 0 Vs 3 Months
A user used oral finasteride and minoxidil for hair loss, seeing new hair growth under a microscope but no visible change. Commenters debated if the growth was real hair or fibers, and the user will update every 90 days.
community Topical Dutasteride. Does it work?
Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.
community Switching RU vehicle due to scalp irritation – anyone tried low-EtOH + squalane / emu oil?
The user is experiencing scalp irritation from using RU58841 with a 70% ethanol and 30% propylene glycol vehicle and is considering switching to a less irritating vehicle, such as 30% ethanol with 70% squalane or emu oil. They are seeking feedback on the effectiveness and irritation levels of these alternative carriers.
community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment
by
MagicBold
in Research
865 upvotes
1 year ago The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.