This review suggests that the inner root sheath of human hair follicles may have broader regulatory roles beyond structural support, potentially impacting processes like folliculogenesis, anagen phase regulation, and immunomodulation.
55 citations
,
February 1985 in “Archives of Dermatology”
In this randomized trial, topical minoxidil treatment resulted in cosmetically acceptable hair growth in 32% of men with hereditary male pattern baldness, with no serious side effects reported.
21 citations
,
September 1979 in “Archives of Otolaryngology-head & Neck Surgery”
This article reviews the use of the Juri procedure for transferring hair to bald scalps, achieving satisfactory cosmetic results in all patients over two years, but reports no new clinical findings.
11 citations
,
October 2007 in “International Journal of Dermatology”
This study describes the epidemiologic, clinical, and etiologic characteristics of alopecia among patients at a dermatology service, identifying tinea and alopecia areata as the most common causes.
A user noticed a sudden baldspot and others suggested it might be alopecia areata, often stress-induced, recommending seeing a dermatologist for steroid injections. Topical minoxidil was mentioned as a successful treatment by one user.
A 26-year-old with a baldspot is seeking advice for hair regrowth, having no treatment history. Suggestions include starting Minoxidil and finasteride to promote growth and reduce hair loss.
A 29-year-old is using 5% topical minoxidil, 5 mg oral minoxidil, 1 mg finasteride, Nizoral shampoo, and weekly microneedling to treat hair loss, reporting significant progress in hair regrowth and hairline improvement. The routine includes applying minoxidil twice daily, managing dead skin with shampoo, and using a baseball cap to maintain hair appearance.
A user experienced significant hair regrowth by switching from finasteride and minoxidil to dutasteride, along with using a leave-in conditioner, rosemary shampoo, and a hair powder drink. They noted improved hair health and thickness, attributing success to this regimen and advising others on similar treatments.
The user has been using minoxidil for 6 months and has seen improvements but still has baldspots. They plan to consult a dermatologist to address their concerns.
Can a hair transplant restore a receding hairline?A transplant can lower or fill a receding hairline if there is enough donor hair. Hair loss behind it usually continues, so plan for the long term with the surgeon.
Can women get hair transplants?Some women are candidates for a hair transplant, but diffuse thinning and a thin donor area limit who is suitable. Clinics say a careful assessment of the cause comes first.
Can PP405 help bald patches caused by stress?PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier; its registered Phase 2 trial (NCT06393452) tested it once daily in 78 adults with pattern hair loss, for safety and tolerability. It is not approved, not for sale, and has not been studied in alopecia areata or stress-related shedding.