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Research

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research Classification of the types of androgenetic alopecia (common baldness) occurring in the female sex

666 citations , September 1977 in “British Journal of Dermatology”

This article presents a classification system for stages of female-pattern androgenetic alopecia to aid early diagnosis and mentions existing systems for rare male-pattern cases, but reports no new clinical results.

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

251 citations , October 2006 in “Plastic and reconstructive surgery/PSEF CD journals”

In this study, platelet plasma growth factors from patients' autologous plasma improved follicular unit yield in baldness surgery by 15.1% compared to control areas.

Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells

research Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells

235 citations , January 2011 in “Journal of Clinical Investigation”

This study found that androgenetic alopecia may involve a defect in the conversion of hair follicle stem cells to progenitor cells, as demonstrated by a reduced presence of progenitor cells in bald scalp samples.

research Balding hair follicle dermal papilla cells contain higher levels of androgen receptors than those from non-balding scalp

227 citations , January 1998 in “Journal of Endocrinology”

This study found that dermal papilla cells from balding scalp hair follicles have significantly higher levels of androgen receptors than those from non-balding follicles, supporting their in vivo androgen response.

research The inheritance of common baldness: Two B or not two B ?

203 citations , November 1984 in “Journal of the American Academy of Dermatology”

This study presents evidence suggesting that androgenetic alopecia is most likely inherited through a polygenic model, challenging the traditional view that it is caused by a simple Mendelian autosomal dominant gene.

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Community Join

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community Going bald is a genuine health issue.

100 upvotes 3 weeks ago

Bald people have a higher risk of skin cancer, especially on the scalp, and wearing a hat is suggested as a solution. Hair loss treatments like Minoxidil, finasteride, and RU58841 are not mentioned in this conversation.

community Bald is sexier than a receding hairline

47 upvotes 1 month ago

Bald men are often seen as more attractive than those with a receding hairline, but opinions vary on whether to embrace baldness or pursue treatments like Minoxidil, finasteride, or RU58841. Confidence and personal comfort are key factors in deciding whether to shave or treat hair loss.

community Bald to back 12 month update. Thanks everyone for the 34K views on previous post.

in Is this regrowth? 177 upvotes 1 year ago

A user shared a 12-month update on their hair transplant, which involved 5700 DHI grafts and cost £4500 at Cosmedica. They also dyed their hair and beard, and users praised the impressive results, suggesting finasteride or dutasteride to prevent further hair loss.

community Balding young is one of the most unfair things ever

371 upvotes 2 months ago

A 19-year-old is frustrated with early balding and is using finasteride and minoxidil, hoping for improvement. Others share similar experiences and suggest additional treatments like microneedling and ketoconazole shampoo.

community Balding for 15 Years, Started Treatment as an Experiment in April — 11 Week Update

170 upvotes 2 months ago

A 37-year-old man has been using a hair loss treatment for 11 weeks, including topical minoxidil, finasteride, tretinoin, dermastamping, and Nizoral shampoo, and is surprised by the progress, noting thicker and longer vellus hairs. He plans to continue and possibly escalate to oral treatments if needed, reporting no side effects so far.

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Learn

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learn Hair Transplant

Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.

Can you go bald after a hair transplant? Yes, you can still go bald after a hair transplant due to thinning native hair.
What causes male pattern baldness? Male pattern baldness is caused by genetic sensitivity to the hormone DHT.

learn Aloe vera

Are random bald spots stressing you out? Aloe vera gel might be your scalp’s natural first aid. Aloe vera gel may help soothe and support scalp health for random bald spots.

learn Centella

Got small bald circles with no warning? Centella creams might calm the area and kickstart new growth. There is no published human trial of Centella asiatica for alopecia areata or any other hair loss; the only hair-related studies are cell-culture work. Community users describe Centella creams as soothing for an irritated scalp, not as regrowth treatments, and a new bald patch needs a doctor's diagnosis first.

learn PP405

Got small bald patches they say are from stress? PP405 sprays could help bring them back to life. PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier; its registered Phase 2 trial (NCT06393452) tested it once daily in 78 adults with pattern hair loss, for safety and tolerability. It is not approved, not for sale, and has not been studied in alopecia areata or stress-related shedding.

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Clinics

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Experts

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