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Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures

research Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures

39 citations , October 2013 in “Plastic and Reconstructive Surgery”

In this study, researchers found that intestine-derived human alpha defensin 5 enhances wound healing, reduces bacterial load, and promotes hair growth in murine burn wound beds by increasing LGR stem cell migration.

Cyanoacrylate Glue as an Effective Skin-Decontamination Method for Hair Follicle Microbiome Sampling: Insights from a Nonhuman Model (Capreolus Capreolus)

research Cyanoacrylate glue as an effective skin-decontamination method for hair follicle microbiome sampling: insights from a nonhuman model (Capreolus capreolus)

June 2026 in “BMC Microbiology”

In this study, researchers demonstrated that using cyanoacrylate glue effectively reduces microbial contamination in biopsy samples from the skin surface of wild roe deer, offering valuable insights for human hair follicle microbiome research despite the nonhuman model.

research Bacterial biofilm in acute lesions of hidradenitis suppurativa

18 citations , June 2016 in “British Journal of Dermatology”

This study found that bacterial biofilms were present in only two out of ten acute hidradenitis suppurativa lesions examined, suggesting a limited primary role for biofilms in early-stage lesions.

research CYSTIC ENDOMETRIAL HYPERPLASIA AND BACTERIAL ENDOMETRITIS ASSOCIATED WITH AN INTRAUTERINE FOREIGN BODY IN A GUINEA PIG WITH OVARIAN CYSTIC DISEASE

7 citations , October 2017 in “Journal of exotic pet medicine”

This case report documents a 3-year-old guinea pig with hormonally active ovarian cysts, cystic endometrial hyperplasia, and bacterial endometritis associated with a uterine foreign body.

research Bacteria and fungi on the surface and within noninflamed hair follicles of skin biopsy specimens from horses with healthy skin or inflammatory dermatoses

7 citations , February 2005 in “Veterinary Dermatology”

This study found that horses with inflammatory skin diseases had a higher prevalence of surface cocci and fungal poroconidia compared to those with healthy skin.

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community DHT is NOT very important for adults, is it?

124 upvotes 4 months ago

A user experienced negative side effects, including low libido and lack of motivation, after using finasteride for hair loss and felt better after stopping it. Others shared similar experiences with finasteride and dutasteride, while some reported no side effects, showing varied individual responses.

community Why the cure is not yet found and why it is always 5 years away? Why no hopes on PP405, GT, KX, Hair cloning, AMP, etc, etc, etc

19 upvotes 1 year ago

Skepticism about hair loss research motivations, suggesting financial interests hinder finding a cure. Mentions treatments like minoxidil, finasteride, and dutasteride, but notes they are not cures.

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 7 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

community Two of the most attractive girls I know are with NW7 guys

in Chat 319 upvotes 1 year ago

Bald men can still attract partners, as personality and confidence often outweigh hair loss. Treatments like finasteride and minoxidil are used, but self-acceptance and personal satisfaction are key.

community What if DHT is not the vilan.

13 upvotes 5 years ago

Hair loss may be influenced more by inflammation, microbiome imbalances, and gut health than DHT. Treatments discussed include minoxidil, finasteride, RU58841, fecal microbiota transplants, and JAK inhibitors.

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learn Stem Cell Factor

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