109 citations
,
March 2011 in “Journal of controlled release” This study found that econazole nitrate delivered via MPEG-dihexPLA micelles significantly increased skin deposition compared to Pevaryl® cream, potentially enhancing drug bioavailability and clinical efficacy.
90 citations
,
May 2019 in “Drugs” Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.
November 2022 in “Indian Journal of Dermatology” This case report describes a 52-year-old woman with erythema annulare centrifugum after using topical luliconazole and oral itraconazole, suggesting a drug-induced reaction confirmed by a positive rechallenge test.
12 citations
,
April 2005 in “Mycoses” This study found that 1-day itraconazole therapy was more effective for acute vulvovaginal candidosis than for recurrent cases, where relapses occurred despite no yeast resistance.
8 citations
,
October 1989 in “International Journal of Dermatology” This review discusses the role of Cytochrome P-450 in dermatology and reports no new clinical results.