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research Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi

41 citations , March 2017 in “PLoS neglected tropical diseases”

Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.

research Androgens Activate Lipogenesis Through an AKT-Independent mTOR Pathway Stimulation and a Limitation of Autophagy in an Androgen-Sensitive Sebocyte Cell Line

April 2019 in “Journal of Investigative Dermatology”

Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.

research Therapeutic Potential of Stem Cell-Derived Exosomes in Hair Regeneration: A Systematic Review

July 2025 in “World Journal of Stem Cells”

Stem cell-derived exosomes could be a promising new treatment for hair regrowth.

research Skin Applications of Cannabidiol: Sources, Effects, Delivery Systems, Marketed Formulations and Safety

1 citations , March 2023 in “Phytochemistry Reviews”

CBD may improve skin and hair health, but its effective use and safety need more research.

research The Interplay Between Finasteride-Induced Androgen Imbalance, Endoplasmic Reticulum Stress, Oxidative Stress, and Liver Disorders in Paternal and Filial Generation

October 2022 in “Biomedicines”

Finasteride in male rats causes liver and metabolic issues in their offspring.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 737 upvotes 3 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community How uninformed the general public is about hair loss

in Chat 313 upvotes 1 year ago

The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 58 upvotes 1 year ago

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

community Bruteforcing alopecia or the new advent of science progress

in Research/Science 21 upvotes 10 months ago

Combining therapies like scyllo-inositol, alpha-ketoglutarate, and autophagy-inducing supplements may enhance hair growth and prevent hair loss. Reporting individual results can accelerate progress in hair loss treatments.

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