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Human Regulatory T Cells: Role in Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers

research Human Regulatory T Cells: Understanding the Role of Tregs in Select Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers

1 citations , January 2023 in “International Journal of Molecular Sciences”

This review explores the role of Tregs in autoimmune skin diseases, transplantation, and skin cancer, and discusses Tregs-based therapies' potential for treating autoimmunity without reporting new experimental results.

research Hair Texture Changes and Regeneration after Chemotherapy may Lead us to Treat Autoimmune Hair Loss

September 2021 in “Zenodo (CERN European Organization for Nuclear Research)”

This review explores the possibility of using the side effects of chemotherapeutic agents for regenerating hair follicles, potentially offering a new treatment avenue for different types of alopecia.

The Therapeutic Potential of Hydroxychloroquine in Treating Autoimmune Alopecias

research O potencial terapêutico da hidroxicloroquina no tratamento de alopecias autoimunes

July 2025 in “Revista Eletrônica Acervo Científico”

This integrative literature review found that hydroxychloroquine may stabilize inflammatory scarring autoimmune alopecias like frontal fibrosing alopecia, especially when combined with other therapies, while its effectiveness in non-scarring alopecias appears inconsistent and is limited to refractory cases.

Autoimmune Associations of Alopecia Areata in Pediatric Population: A Study in a Tertiary Care Center

research Autoimmune associations of alopecia areata in pediatric population - A study in tertiary care centre

April 2020 in “IP Indian journal of clinical and experimental dermatology”

This study explores autoimmune associations in pediatric patients with alopecia areata at a tertiary care center but reports no new clinical findings.

The Use of Auto-Antibody Testing in the Evaluation of Interstitial Lung Disease: A Practical Approach for the Pulmonologist

research The use of auto-antibody testing in the evaluation of interstitial lung disease (ILD) – A practical approach for the pulmonologist

26 citations , February 2016 in “Respiratory Medicine”

This article reviews strategies for serological testing in diagnosing ILD linked to systemic rheumatic diseases and introduces a potential diagnostic algorithm for pulmonologists, while noting further validation is needed.

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Community Join

5 / 205 results

community is there anything that stops hair loss?

8 upvotes 1 year ago

A user is experiencing rapid hair loss and has been diagnosed with telogen effluvium by multiple dermatologists, but doubts the diagnosis due to the severity and speed of the hair loss. They are considering various treatments like spironolactone, estradiol, and possibly finasteride, while also exploring the possibility of hormonal imbalances or autoimmune issues.

community No idea what's causing my hair thinning

in Chat 2 upvotes 1 year ago

The user is experiencing diffuse hair thinning despite using finasteride and oral minoxidil, with no hairline recession or bald spots. Suggestions include checking for telogen effluvium, considering a JAK inhibitor for potential autoimmune issues, and conducting further tests to rule out other causes.

community Diffuse thinning is so fucked. Change in my from March til now

in Finasteride/Dutasteride 417 upvotes 1 year ago

The user experienced significant hair thinning despite using finasteride and minoxidil, leading to concerns about whether it's a temporary shed or a more serious issue. They plan to start using RU58841 and are advised to consult a doctor to rule out other causes like autoimmune disorders.

community Long-term finasteride users: Have you noticed phases of improvement and worsening?

in Treatment 9 upvotes 1 year ago

The conversation is about long-term finasteride use for hair loss, with users discussing periods of improvement and worsening, and considering switching to dutasteride. Other treatments mentioned include minoxidil, red light therapy, microneedling, and scalp massaging.

community Please take a vitamin & hormone test

255 upvotes 1 year ago

Checking vitamin and hormone levels is important for addressing hair loss, as deficiencies in vitamin D, zinc, and iron can affect hair growth. Treatments like finasteride, minoxidil, and vitamin supplements are used, but addressing deficiencies is crucial for effectiveness.

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Learn

7 / 801 results

learn Scalp Micropigmentation

Is scalp micropigmentation safe? Providers describe scalp micropigmentation as low-risk when a trained practitioner uses sterile single-use equipment, but that is a provider claim rather than a regulatory finding: pigment allergy, infection and colour change are documented risks of cosmetic tattooing.

learn Cetirizine

Could cetirizine help control autoimmune triggers in alopecia areata? No published trial has tested cetirizine in alopecia areata; one registered trial has not reported results. Small trials in pattern hair loss report modest benefit, so any use for alopecia areata is off-label and unproven.

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Microneedling

technique to create small wounds in skin to activate collagen production and hair growth

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

What is tofacitinib, and why is it discussed in relation to autoimmune-related hair loss such as alopecia areata? Tofacitinib is a prescription JAK inhibitor approved for rheumatoid arthritis, psoriatic arthritis and ulcerative colitis — not for alopecia areata. It is discussed for hair loss because a 2014 case report and a 2016 open-label trial reported regrowth in severe alopecia areata, but that use is off-label, the regrowth relapsed after stopping, and the drug carries an FDA boxed warning.