Search

for
Search:

Research

5 / 1000+ results

research Human Skin is a Steroidogenic Tissue: Steroidogenic Enzymes and Cofactors Are Expressed in Epidermis, Normal Sebocytes, and an Immortalized Sebocyte Cell Line (SEB-1)

289 citations , May 2003 in “Journal of Investigative Dermatology”

This study demonstrates that human skin is capable of steroid hormone synthesis, but its role in androgenic skin disorders like acne and alopecia is yet to be clarified.

research Mice lacking desmocollin 1 show epidermal fragility accompanied by barrier defects and abnormal differentiation

195 citations , November 2001 in “The Journal of Cell Biology”

This study found that desmocollin 1 is crucial for strong adhesion and barrier maintenance in the mouse epidermis, with its absence leading to skin and hair issues resembling chronic dermatitis.

research Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes

171 citations , July 2007 in “Journal of Investigative Dermatology”

The researchers reported that DHT-inducible DKK-1 may play a significant role in DHT-driven balding by inhibiting hair follicle cell growth and promoting apoptosis in androgenetic alopecia.

research PUVA treatment of alopecia areata partialis, totalis and universalis: audit of 10 years' experience at St John's Institute of Dermatology

105 citations , December 1995 in “British journal of dermatology/British journal of dermatology, Supplement”

This retrospective study concluded that PUVA treatment is generally ineffective for alopecia areata, with low effective success rates for partialis, totalis, and universalis types.

research In Human Skin, UVB Initiates Early Induction of IL-10 Over IL-12 Preferentially in the Expanding Dermal Monocytic/Macrophagic Population

101 citations , July 1998 in “Journal of Investigative Dermatology”

This study found that UV exposure in human skin induces IL-10 production by macrophages, while Langerhans cells are depleted and their IL-12 production is downregulated.

View more "at-10" in research →

Community Join

5 / 1000+ results

community (22m) 10 month 1mg Finastride results.

6 upvotes 1 week ago

The user is not satisfied with the results after 10 months of using finasteride and plans to start using topical minoxidil for hair regrowth. Other users suggest considering oral minoxidil, microneedling, and possibly switching to dutasteride for better results.

community Almost 10 months into dut/oral min and it’s getting worse (with pics)

132 upvotes 1 month ago

A user switched from finasteride and topical minoxidil to dutasteride and oral minoxidil, but experienced worsening hair loss and thinning. Suggestions included returning to finasteride, adding finasteride to the current regimen, or considering other factors like genetics or additional causes of hair loss.

community 10 month progress. I feel stalled at the very least.

in Progress Pictures 26 upvotes 1 month ago

The user has been using 1.2 mg Finasteride and 3 mg Minoxidil orally for 10 months, initially seeing progress but now feeling stalled. Suggestions include adding microneedling, Ketoconazole shampoo, or considering a hair transplant.

community 23M 10.5 months into 3-6mg Minoxodil 1mg Finasteride. Realistic, Limited Progress despite HIGH DOSE.

9 upvotes 4 months ago

A 23-year-old male is experiencing aggressive hair loss despite using 1mg finasteride and 4.5mg minoxidil, with limited progress and side effects like fluid retention. Suggestions include trying dutasteride, microneedling with topical minoxidil, and considering hair systems or a transplant in the future.

community Almost 10 months progress on oral min, topical min, oral fin

in Progress Pictures 7 upvotes 4 months ago

The user has seen good progress in hair density after almost 10 months using 0.6 mg oral minoxidil, 1.25 mg oral finasteride every other day, and topical minoxidil twice daily, along with weekly derma stamping. They experienced side effects with higher doses of minoxidil and encourage others to try these treatments.

View more "at-10" in community →

Learn

2 / 801 results

learn Polyquaternium-10

learn TDM-105795

What is TDM-105795, and why is it being studied as a potential product for hair loss and hair growth support? TDM-105795 is an experimental drug aimed at treating androgenetic alopecia to promote hair growth.
How is TDM-105795 used in hair-related products, and is it being explored as a topical treatment, an oral option, or both? TDM-105795 is not sold in any hair product — it is an unapproved experimental compound. The public trial registry shows it has been studied only as a topical scalp solution, in three completed company trials (the largest a 71-participant, 16-week Phase 2); no oral programme is registered, and no peer-reviewed publication exists.
What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.
All 5 questions on TDM-105795 →

View more "at-10" in learn →

Experts

2 / 20 results

Clinics

6 / 21 results

All 21 clinic results →