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research Androgen Binding Profiles of Two Distinct Nuclear Androgen Receptors in Atlantic Croaker (Micropogonias Undulatus)

58 citations , June 2000 in “The Journal of Steroid Biochemistry and Molecular Biology”

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

research Methylation And Decreased Expression Of 5-Alpha Reductase 2 In Human Prostate Samples: Implications For Resistance To Therapy For BPH

March 2010 in “The Journal of Urology”

Methylation of the 5-AR2 gene may cause resistance to Finasteride in BPH patients.

research Methylation of CpG Islands in Promoter of Type 2 5-Alpha Reductase and Implications of Finasteride Resistance for BPH Therapy

March 2016 in “European Urology Supplements”

Methylation in specific gene region causes finasteride resistance in some BPH patients.

research Systematic Review and Meta-Analysis of Randomized Trials and Cohort Studies of Mycophenolate Mofetil in Lupus Nephritis

137 citations , December 2006 in “Arthritis Research & Therapy”

Mycophenolate mofetil is safer and more effective than cyclophosphamide for treating lupus nephritis.

research Rodent Models in Placental Research: Implications for Fetal Origins of Adult Disease

7 citations , January 2022 in “Animal Reproduction”

Using rodents for research shows that health problems in the womb can cause diseases later in life.

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community Hair loss causes are still a myth.

in Chat 17 upvotes 4 years ago

The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.

community Is it possible for Dutasteride to make one mentally slow?

in Chat 22 upvotes 1 year ago

Dutasteride may cause mental fog, vision blurriness, and sleep issues. Users suggest trying topical versions of the drug to mitigate side effects.

community 8 years of Finasteride and Minoxidil (includes a photo)

in Update 71 upvotes 2 years ago

User has used Finasteride, Minoxidil, and derma roller for 8 years to treat hair loss but is still losing the battle. Others suggest trying Dutasteride, oral Minoxidil, RU58841, or considering a hair transplant.

community Explanation for "dutasteride destroyed my hair"

in Finasteride/Dutasteride 7 upvotes 1 year ago

Dutasteride can drastically reduce sebum production, leading to dryer hair and shedding. Alternating shampoos and periodic silica supplementation can improve hair quality and thickness.