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      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn GT20029

      research compound made to degrade androgen receptors in scalp

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      community 2 Years on Fin — Early Gains, Acne Flare, and Ongoing Scalp Sensitivity

      in Finasteride  149 upvotes 17 hours ago
      The user has been on finasteride for over two years, experiencing early hair regrowth, acne, and scalp sensitivity, but now faces thinning hair and questions about dosage and long-term effectiveness. They also used retinal to help with acne and are seeking advice on whether to adjust their finasteride dose.

      community Ru58841 made my hair worse

      in General  138 upvotes 2 months ago
      RU58841 worsened hair condition, causing thinning and unusual patterns. The user stopped using it two months ago but hasn't seen recovery, and there's speculation about androgen receptor upregulation.

      community Finasteride + Cialis together long term?

      in Treatment  3 upvotes 10 months ago
      The user has been on 1mg finasteride for a year, experiencing low libido and moderate erectile issues. They are considering using Cialis daily with finasteride long term to address these side effects.
      Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      in Treatments  451 upvotes 10 months ago
      Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.