This study found that a 2% spironolactone cream, applied topically for 3 months, did not reduce hair growth in patients with facial hirsutism compared to untreated areas.
8 citations
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August 2012 in “Clinical, cosmetic and investigational dermatology” In this study, Doublebase gel was more effective in maintaining and increasing skin hydration compared to Aqueous cream BP, with higher patient satisfaction and preference for future use.
19 citations
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December 2013 in “European journal of pharmaceutics and biopharmaceutics” This study found that encapsulated Garcinia mangostana Linn extract in a cream base penetrated more deeply and homogeneously into porcine ear skin compared to other formulations.
June 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This study reported the preparation of stable oil-in-water nanoemulsions that effectively incorporate ceramide-like molecules and minoxidil, suggesting these formulations may enhance distribution and availability of hydrophobic compounds in cosmetic applications.
30 citations
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April 1990 in “Clinical Pharmacology & Therapeutics” This study found that coadministering minoxidil with tretinoin cream increased minoxidil absorption nearly threefold in healthy males, attributed to increased stratum corneum permeability.