December 2024 in “Signal Transduction and Targeted Therapy” In this study published in Nature, researchers explored how hair follicle stem cells manage apoptotic cell clearance while maintaining their regenerative roles, identifying significant molecules involved in sensing and engulfing dying cells to sustain tissue health.
2 citations
,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that stem cells can temporarily act as non-professional phagocytes during hair cycle regeneration by clearing apoptotic cells through a process requiring local lipids and retinoids for activation, providing insights into their dual role in maintaining tissue integrity.
March 2026 in “Frontiers in Immunology” This review highlights the complex role of leukocyte migration in both driving inflammation and facilitating its resolution, suggesting that targeted modulation of this process could improve therapeutic strategies for inflammatory diseases.
December 2014 in “TDX (Tesis Doctorals en Xarxa)” This study suggests that while cellular senescence impairs epidermal stem cells in aging, it also serves an essential role during embryonic development, highlighting its dual functional nature.
35 citations
,
July 2022 in “Frontiers in Integrative Neuroscience” This review discusses the neuroprotective potential of formononetin, especially for neurological diseases, and reports no clinical results; the authors suggest its promise for developing central nervous system drugs.