8 citations
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September 2022 in “Biointerface Research in Applied Chemistry”
This review examines the pharmacological potential of quinoline alkaloids from Cinchona bark for developing new drugs and cosmetics but reports no new findings.
January 2025 in “Institutional Repositories DataBase (IRDB)”
This study observed that topical application of maslinic acid stimulated hair growth in mice comparably to minoxidil, possibly through the Wnt/β-catenin pathway and involving ciliary gene activity, highlighting increased levels of trichogenic gene expression and protein levels.
July 2025 in “ACS Pharmacology & Translational Science”
In this study, maslinic acid applied topically was observed to stimulate hair growth in mice comparably to minoxidil, primarily activating pathways like Wnt/β-catenin, and suggesting a link between hair growth and cilia activity.
This study found that patients with vitiligo and alopecia areata had significantly higher serum granulysin levels compared to healthy controls, indicating a potential pathogenic role and suggesting that elevated levels may serve as a biomarker for monitoring disease activity, particularly in active vitiligo cases.
This study found that a topical gel formulation containing rice water demonstrated in vitro antioxidant activity and elastase inhibition, suggesting its potential as an anti-aging skincare ingredient.
Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.
Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.