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research Antiviral Drugs Prolong Survival in Murine Recessive Dystrophic Epidermolysis Bullosa
Antiviral drugs, especially daclatasvir, may be a new treatment for a rare skin disease, improving survival and reducing symptoms in mice.
research Fever, Maculopapular Rash, and Severe Aphthous Stomatitis in a Renal Transplant Patient
The patient improved after antiviral treatment for a viral infection.
research Therapeutics for COVID-19 and Post COVID-19 Complications: An Update
New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.
research Irreversible Alopecia Universalis During Treatment With Pegylated Interferon-Ribavirin for Chronic Hepatitis C Virus Infection: Case Report and Literature Review
A man lost all his hair permanently after hepatitis C treatment, a side effect not seen before.
research Host-Directed FDA-Approved Drugs with Antiviral Activity Against SARS-CoV-2 Identified by Hierarchical In Silico/In Vitro Screening Methods
In response to the COVID-19 pandemic, researchers conducted a study to identify FDA-approved drugs that could be repurposed as antiviral treatments against SARS-CoV-2. They employed a hierarchical in silico/in vitro screening method, which combined virtual and biological screening to efficiently identify host-directed therapies. The study focused on host-based targets related to viral entry and led to the identification of five potentially repurposable drugs: cepharantine, clofazimine, metergoline, imatinib, and efloxate, which showed potential in interfering with viral entry.
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