46 citations
,
December 2014 in “Epilepsy & behavior” This study found that weight gain and alopecia were the most common cosmetic side effects of AEDs, with valproic acid and pregabalin being particularly associated with these effects.
8 citations
,
April 2022 in “International Journal of Environmental Research and Public Health” This study found that pediatric epilepsy patients on polytherapy experienced more adverse drug reactions compared to those on monotherapy, despite improved seizure control with polytherapy.
12 citations
,
September 2002 in “Epilepsia” This paper discusses the methods and challenges of postmarketing surveillance for new antiepileptic drugs, emphasizing the necessity of such data collection to identify adverse effects and assess drug effectiveness beyond initial trials.
6 citations
,
April 2019 in “Russkij žurnal detskoj nevrologii” This study found that neuroendocrine and reproductive disorders were most commonly reported in women with epilepsy taking valproic acid, while newer antiepileptic drugs resulted in more favorable outcomes.
1 citations
,
April 2015 in “Russkij žurnal detskoj nevrologii” This study found that young women with epilepsy experienced various neuroendocrinal and reproductive side effects, with valproic acid showing the highest risk for teratogenic effects and associated disorders.