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Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs

research Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs

11 citations, October 2019 in “Cancers”

Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.

research An Exclusive Review of Melatonin Effects on Mammalian Melanocytes and Melanoma

3 citations, November 2022 in “Experimental dermatology”

Melatonin may inhibit melanoma growth and has potential as a cancer therapy aid, but its effects on human skin pigmentation need more research.

Hair Growth Promoting and Anticancer Effects of p21-Activated Kinase 1 (PAK1) Inhibitors Isolated from Different Parts of Alpinia Zerumbet

research Hair Growth Promoting and Anticancer Effects of p21-Activated Kinase 1 (PAK1) Inhibitors Isolated from Different Parts of Alpinia Zerumbet

13 citations, January 2017 in “Molecules”

Compounds from Alpinia zerumbet may help with hair regrowth and cancer treatment by targeting PAK1.

research Drug Repurposing: Hypothesis, Molecular Aspects, and Therapeutic Applications

39 citations, April 2020 in “IntechOpen eBooks”

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

research Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance

7 citations, January 2023 in “Journal of Hematology & Oncology”

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

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Community Join

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community If you had to choose one ? Fin or min ?

in Product 99 upvotes 5 months ago

The conversation is about choosing between finasteride and minoxidil for hair loss treatment. Most users prefer finasteride, citing its effectiveness in stopping hair loss, while some mention using both for better results.

community This sub in a nutshell when it comes to medicine. Oral Minoxidil isn’t that bad

in Chat 446 upvotes 1 year ago

The post and conversation are about the use of oral Minoxidil (Min), Finasteride (Fin), and RU58841 for hair loss treatment, with mixed opinions on their safety and effectiveness.

community Keratin microspheres - breakthrough

in Research/Science 13 upvotes 8 months ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community A systematic bro-science review of DHT, 5AR, neurosteroids, sexual health and 5AR inhibitors

in Research/Science 37 upvotes 2 years ago

Hair loss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.

community My hair loss journey, natural DHT blocker first then Finasteride 1mg every day.

in Progress Pictures 152 upvotes 1 month ago

The user experienced hair regrowth and stopped hair loss using a natural DHT blocker and later finasteride, despite initial side effects. They plan to add topical minoxidil to address remaining thin spots.

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