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This study found that antiandrogenic compounds in Curcuma aeruginosa, including germacrone, degrade rapidly at high temperatures but are more stable when solubilized in PEG-40.

This study found that Ganoderma lucidum extracts showed weak 5alpha-reductase inhibition but significantly inhibited prostate cell proliferation and testosterone-driven prostate growth in rats, suggesting potential as an ingredient for treating androgen-induced diseases.

This literature review suggests that herbal extracts show promise as antiandrogenic agents for androgen-related conditions, potentially offering a natural alternative with fewer side effects than synthetic medications.

This study found that Lepidium sativum leaf extract significantly downregulated VEGF, TNF-α, and SRD5A2 gene expressions in HaCaT cells, suggesting potential benefits for inflammatory and androgen-dependent skin disorders.

This study identified Aquilaria sinensis and Piper cubeba as tropical plants with potential anti-androgenic and anti-estrogenic properties that could help prevent or alleviate benign prostatic hyperplasia and prostate cancer.