This review suggests that metformin, known for its antidiabetic uses, may benefit chronic inflammatory skin diseases like acne vulgaris, hidradenitis suppurativa, and rosacea due to its multiple therapeutic properties, although more research is needed to confirm its efficacy in dermatology.
June 2024 in “International Journal of Dermatology”
In this article, a case report examines the use of topical metformin 10% cream for treating central centrifugal cicatricial alopecia, contributing to existing literature on potential treatments for this condition.
This review discusses the use of low-dose oral minoxidil for patterned hair loss and reports it may offer improved compliance and safety compared to topical minoxidil, but provides no new clinical findings.
2 citations
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March 2019 in “American journal of physiology. Renal physiology./American journal of physiology. Renal physiology”
This paper discusses the potential of targeting fibrosis in addressing lower urinary tract symptoms associated with benign prostatic hyperplasia, but it provides no new clinical findings and highlights the need for further research.
Topical caffeine is suggested as a beneficial adjunct treatment for hair growth due to its anti-fibrotic, anti-inflammatory, antioxidant, and other properties. There is skepticism about its effectiveness, especially at low concentrations like in Alpecin liquid.
Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotictreatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.
Resveratrol and fisetin, found in red wine and strawberries, may promote hair growth by affecting hair follicle cells. Users discuss various treatments, including natural remedies like saw palmetto and topical applications, with mixed opinions on their effectiveness compared to pharmaceuticals like finasteride.
The user switched from finasteride and minoxidil to dutasteride, saw palmetto, and a finasteride lotion but hasn't seen improvement in hair loss after six months. Suggestions include being patient, considering a hair transplant, and adding treatments like microneedling, ketoconazole shampoo, and topical anti-androgens.
Dutasteride treatment may decrease sperm concentration, but levels remain above WHO recommendations and recover after discontinuation. The study has limitations, including small sample size and lack of pre-treatment sperm data, and does not assess other fertility factors.