11 citations
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December 2011 in “Revista Brasileira de Farmacognosia” In this animal study, petroleum ether and ethanolic extracts of Abrus precatorius seeds appeared to reverse androgen-induced alopecia in male albino rats by inhibiting the 5α-reductase enzyme, similar to finasteride.
13 citations
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August 2018 in “Journal of Molecular and Cellular Cardiology” This study demonstrated that finasteride treatment reduced cardiac dysfunction and hypertrophic remodeling in mice after myocardial infarction, suggesting potential as a therapeutic strategy for heart failure.
43 citations
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August 2021 in “Journal of Orthopaedic Translation” This study explored a dual-functional dressing with quaternized chitosan and magnesium, finding it enhanced wound healing and had strong antibacterial effects against drug-resistant bacteria in diabetic rat models with infected foot ulcers, suggesting promise for diabetic foot ulcer treatment.
November 2018 in “Journal of Molecular and Cellular Cardiology” This study found that finasteride improved cardiac function and reduced remodeling after myocardial infarction in mice.
27 citations
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April 2008 in “Journal of Biological Chemistry” This study found that simvastatin interfered with insulin-induced VEGF expression and keratinocyte proliferation during skin repair in mice, effects that could be reversed by mevalonate.