April 2021 in “IntechOpen eBooks” This article discusses the need to investigate long-term effects of androgen manipulations independently of current levels, referencing Post-finasteride Syndrome as a relevant clinical example, and reports no new results.
27 citations
,
January 1984 in “Pharmacology & Therapeutics” This review discusses androgen manipulation strategies for conditions like benign prostatic hyperplasia and prostatic carcinoma but reports no new clinical results.
7 citations
,
January 1994 in “Annual Reports in Medicinal Chemistry” This review discusses hormonal manipulation for conditions like prostatic disorders and skin issues and highlights promising treatments like casodex and finasteride, but it reports no new clinical results.
December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” This study found that manipulating 5αR2 activity in human hepatocytes in vitro can regulate lipogenesis, with potential clinical implications for patients taking 5αR inhibitors.
September 2025 in “Deleted Journal” This study found that in vitro environments simulating testosterone levels in elderly males, testosterone and its metabolite DHT significantly reduced macrophages' ability to phagocytize MRSA and Pseudomonas aeruginosa, suggesting AR manipulation and inhibiting testosterone-DHT conversion might help fight wound infections in the elderly.