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research Female pattern hair loss may be triggered by low oestrogen to androgen ratio.

9 citations , March 2008 in “PubMed”

This study observed that women with female pattern hair loss had a significantly lower ratio of estradiol to free testosterone compared to healthy controls, suggesting a potential hormonal trigger for hair loss.

research Finasteride-Induced Gynecomastia in a 62-Year-Old Man

15 citations , June 1995 in “The American Journal of the Medical Sciences”

This study describes a case where finasteride treatment for benign prostatic hypertrophy was associated with gynecomastia in a 62-year-old man, which resolved after the drug was discontinued.

research Polymorphisms in Genes Involved in Steroidogenesis in the Development of Severe Acne

September 2021 in “International Journal of Biomedicine”

This study found that SNPs in the MVK, ARPC1B, and CA2 genes may indicate a genetic predisposition for severe acne related to steroidogenesis.

research Sex hormone levels and body hair growth in !Kung San and Kavango men from Namibia

25 citations , October 1993 in “American Journal of Physical Anthropology”

This study observed that in Namibian/Southern African men, hormone levels, particularly estradiol, influence the growth of body hair, with different effects noted in various ethnic groups.

research CONTRACEPTION AND THE SKIN

2 citations , August 1987 in “Australasian Journal of Dermatology”

This review discusses skin diseases related to contraceptive use, reporting potential issues with oral contraceptives and infrequent reactions to mechanical or barrier methods without new clinical findings.

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community My Theory Of Androgenic Alopecia

16 upvotes 10 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community Serious question, is there nothing that can be done if Dutasteride doesn’t help to stop my hair loss?

60 upvotes 4 years ago

A 25 year old male who has been using finasteride and dutasteride for two years to treat his hair loss, with no success. Other treatments such as oral minoxidil, topical anti-androgens, RU58841, latanoprost, topical estrogen, CB 03 01, microneedling, keto 2% shampoo, vitamin D, Omega 3, B vitamins and probiotics were discussed.

community Is ED after taking Fin or Dut caused by less DHT or an increase in Estrogen/Estradiol

3 upvotes 2 years ago

Finasteride and dutasteride may cause erectile dysfunction due to reduced DHT, affecting nitric oxide and sexual function. Some suggest using aromatase inhibitors to address side effects, while others believe individual sensitivity to DHT reduction varies.

community Someone told me it is the increase in estradiol and estrogen from more free t that makes dht blockers work?

6 months ago

Finasteride and its effects on hair loss, with discussions on the role of estradiol and estrogen. Users debate whether increased estrogen from DHT blockers contributes to hair regrowth, with concerns about potential side effects like chemical castration.

community Finasteride doubled my testosterone & estrogen

in Chat 265 upvotes 10 months ago

Finasteride increased testosterone and estrogen, stopped hair loss, and promoted regrowth. Users discussed side effects like libido changes and considered adding minoxidil and aromatase inhibitors.

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Learn

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learn Overview

learn Alfatradiol

a synthetic estrogen used topically as an anti-androgen

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

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