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research Cellular Activity in the Dermis Surrounding the Hair Bulb in Alopecia Areata

25 citations , October 1975 in “Journal of Cutaneous Pathology”

This study found that in alopecia areata, hair bulbs are blocked in an early growth stage due to impaired metabolic function in the surrounding connective tissue, hindering hair growth.

research Correlation of proteolytic activities of organ cultured intact mouse skin with defined hair cycle stages

28 citations , June 1994 in “Journal of Dermatological Science”

This study found that proteolytic activities in murine skin vary with hair cycle stages, with significant collagenase activity during the early anagen phase.

Topical Application of Cyclosporin A Induces Rapid Remodeling of Damaged Anagen Hair Follicles in Cyclophosphamide-Administered Mice

research Topical application of cyclosporin A induces rapid-remodeling of damaged anagen hair follicles produced in cyclophosphamide administered mice

24 citations , September 2001 in “Journal of Dermatological Science”

This study found that cyclophosphamide-induced hair follicle damage in C3H mice could be remodelled into intact anagen hair follicles with topical cyclosporin A, especially in anagen IV stage follicles.

research Hair-cycle dependent differential expression of ADAM 10 and ADAM 12

5 citations , January 2009 in “Dermato-endocrinology”

This study suggests that ADAM 10 and 12 proteases may play important roles in the regulation of hair cycling through their expression patterns in hair follicle structures.

research [Proliferation behavior of the anagen hair bulb in androgenetic alopecia before and after local administration of 17 alpha- propylmesterolone–DNA flow cytophotometry studies].

December 1990 in “PubMed”

This study found that topical application of 17 alpha-propylmesterolone significantly increased proliferative activity in hair matrix cells in men with androgenetic alopecia.

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community Amplifica: Hope or Cope? A Review of Their Pipeline

9 upvotes 4 weeks ago

Amplifica's AMP-303 showed a modest increase in hair growth, but results were inconsistent and potentially misleading. Hyaluronic acid and osteopontin are being explored for hair growth, with varying effects on different hair types and conditions.

community Any dutasteride succes stories?

in Finasteride/Dutasteride 31 upvotes 1 year ago

Dutasteride is effective for many in reducing hair loss and promoting regrowth, often with fewer side effects than finasteride. Combining it with minoxidil is commonly seen as a successful strategy, though results may take several months.

community Reminder: NURTURE those dormant hair follicles for as long as you can until PP405 comes out in 2028-2030

in Treatment 191 upvotes 9 months ago

PP405 is anticipated as a future treatment for dormant hair follicles, but its effectiveness and safety are uncertain. Current treatments include oral minoxidil and microneedling, with some avoiding finasteride due to side effects.

community The Finasteride Shed is real.

in Finasteride/Dutasteride 159 upvotes 1 year ago

Increasing finasteride dosage can cause significant hair shedding initially. Users suggest adding minoxidil or switching to dutasteride for better results.

community Answers to the most frequently asked questions

in Finasteride/Dutasteride 74 upvotes 1 year ago

Finasteride and dutasteride must be taken continuously to prevent hair loss, and minoxidil should also be used long-term. Patience is needed as results from these treatments can take months to over a year to appear.

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58
Hair Transplant Surgeon
Dr. W. Patrick Coleman, IV, MD
Metairie, LA, United States

Dr. W. Patrick Coleman, IV, MD