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GlossaryALA-PDT (Aminolevulinic Acid Photodynamic Therapy)

uses light-activated aminolevulinic acid to treat skin conditions

ALA-PDT, or Aminolevulinic Acid Photodynamic Therapy, is a medical treatment that uses a photosensitizing agent called aminolevulinic acid (ALA) combined with light exposure to target and destroy abnormal cells. This therapy is commonly used for treating certain skin conditions, including actinic keratosis and some types of skin cancer, by applying ALA to the affected area and then activating it with a specific wavelength of light, leading to the selective destruction of the abnormal cells.

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Treatment of Androgenetic Alopecia with 5-Aminolevulinic Acid Photodynamic Therapy: A Randomized, Placebo-Controlled, Split-Scalp Study of Efficacy and Safety

research Treatment of Androgenetic Alopecia with 5-Aminolevulinic Acid Photodynamic Therapy: A Randomized, Placebo-Controlled, Split-Scalp Study of Efficacy and Safety

2 citations , August 2021 in “Photodiagnosis and Photodynamic Therapy”

Using 5-aminolevulinic acid photodynamic therapy for hair loss didn't increase hair growth but slightly reduced scalp oiliness, and it was safe with mild side effects.

research Successful In Situ 5-Aminolevulinic Acid Photodynamic Therapy in a 53-Year-Old Female with Cutaneous Squamous Cell Carcinoma

1 citations , September 2025 in “Journal of Zhejiang University SCIENCE B”

Photodynamic therapy successfully treated skin cancer in a 53-year-old woman.

research Topical ALA-Photodynamic Therapy for Acne Can Induce Apoptosis of Sebocytes and Down-Regulate Their TLR-2 and TLR-4 Expression

37 citations , January 2011 in “Annals of Dermatology”

ALA-photodynamic therapy helps reduce acne by causing acne cell death and lowering certain skin protein levels.

research The Use of Photodynamic Therapy for Treatment of Acne Vulgaris

29 citations , January 2007 in “Dermatologic Clinics”

Photodynamic Therapy is an effective treatment for mild to severe acne.

research Chronic Crusted Scalp Lesion of an Elderly Male

2 citations , December 2017 in “Skin appendage disorders”

An elderly man's non-healing scalp lesion was successfully treated with a strong topical steroid.

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community How does low level laser therapy?

in Chat 5 upvotes 7 months ago

Low-level laser therapy (LLLT) is debated for hair regrowth, with some users suggesting it should be combined with treatments like minoxidil and finasteride for effectiveness. Many users express skepticism about LLLT's efficacy and cost, emphasizing the need for the correct wavelength and quality devices.