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Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions

research Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions

14 citations, February 1998 in “Bioorganic & Medicinal Chemistry Letters”

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

research Serum Metabolomics Study of Polycystic Ovary Syndrome Based on Liquid Chromatography–Mass Spectrometry

71 citations, January 2014 in “Journal of Proteome Research”

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Palladium Nanoparticles on a Pyridinium Supported Ionic Liquid Phase: A Recyclable and Low-Leaching Palladium Catalyst for Aminocarbonylation Reactions

research Palladium Nanoparticles on a Pyridinium Supported Ionic Liquid Phase: A Recyclable and Low-Leaching Palladium Catalyst for Aminocarbonylation Reactions

15 citations, January 2020 in “RSC advances”

The new palladium catalyst is effective and reusable for making pharmaceutical ingredients.

research New Fluorogenic Probes for Neutral and Alkaline Ceramidases

5 citations, June 2019 in “Journal of lipid research”

New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.

research Facile One-Pot Synthesis of Substituted Hydantoins from Carbamates

3 citations, August 2017 in “Synlett”

Scientists in India found a safer and efficient way to make a type of medicine called hydantoins from carbamates, which also worked well in making the seizure medicine, Ethotoin.

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Community Join

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community hmi115 is coming. Prepare yourselves for what's coming

in Technology 106 upvotes 1 year ago

The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

community M19 shed after 1yr on dutasteride

in Finasteride/Dutasteride 23 upvotes 1 month ago

A 19-year-old male experienced hair shedding after one year on dutasteride and is considering adding topical minoxidil despite scalp itching. Users suggest continuing dutasteride, maintaining a consistent hair routine, and possibly increasing minoxidil dosage.

community Topical Dutasteride & Microneedling Works

in Finasteride/Dutasteride 5 upvotes 2 months ago

Topical dutasteride, especially at higher concentrations, can be effective for hair loss when combined with microneedling to enhance absorption. Users discuss the side effects of finasteride and dutasteride, with some preferring topical treatments to avoid systemic side effects.

community I'm starting topical fin/min 3x week tomorrow. My anxiety levels are through the roof.

in Treatment 14 upvotes 7 months ago

A user is starting topical finasteride and minoxidil 3 times a week for hair loss and is experiencing high anxiety about the treatment's effectiveness and potential side effects. They are also taking vitamin D3 daily and are concerned about the application method and possible shedding.

community 30yo, Dut 0.5mg/day, min 5% once/day, biotin 1000mg 3times/week, derma once/week, anaphase+ 2times/week, nizoral 2 times/week

in Progress Pictures 215 upvotes 10 months ago

A 30-year-old uses Dutasteride, Minoxidil, biotin, dermarolling, Anaphase+ shampoo, and Nizoral for hair loss. Some commenters question the need for such extensive treatment given the minimal hair loss.

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