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Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions

research Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions

14 citations , February 1998 in “Bioorganic & Medicinal Chemistry Letters”

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

research Synthesis of Mimics of Steroid A Ring as Potential Enzyme Inhibitors

September 2002 in “Research Repository (Kingston University London)”

Mimicking the steroid A-ring may help create effective enzyme inhibitors for prostate disease treatment.

research Design, Synthesis, and Structure-Activity Relationship Studies on Steroidal Aromatase and 5α-Reductase Inhibitors as Anti-Tumor Agents

December 2013 in “Estudo Geral (Universidade de Coimbra)”

Modified steroidal inhibitors showed promise in treating hormone-dependent cancers.

research Serum Metabolomics Study of Polycystic Ovary Syndrome Based on Liquid Chromatography–Mass Spectrometry

71 citations , January 2014 in “Journal of Proteome Research”

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

research Design, Synthesis and Anxiolytic Activity Evaluation of N-Acyltryptophanyl-Containing Dipeptides, Potential TSPO Ligands

16 citations , November 2018 in “Medicinal Chemistry”

The compound GD-23 may reduce anxiety like diazepam by targeting the TSPO receptor.

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Community Join

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community Don't use PP405 from everychem. it is likely fake.

in Research/Science 65 upvotes 8 months ago

PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.

community hmi115 is coming. Prepare yourselves for what's coming

in Technology 108 upvotes 2 years ago

The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

community Progress and results of 3 months of Fin+ Min

in Progress Pictures 659 upvotes 2 months ago

A user shared their 3-month progress using topical Minoxidil 5% and oral Finasteride 1mg daily, along with ketoconazole shampoo and derma stamping, reporting significant hair growth without side effects. Some users doubted the results, while others discussed potential side effects of Finasteride and alternative treatments.

community I'm starting topical fin/min 3x week tomorrow. My anxiety levels are through the roof.

in Treatment 14 upvotes 1 year ago

A user is starting topical finasteride and minoxidil 3 times a week for hair loss and is experiencing high anxiety about the treatment's effectiveness and potential side effects. They are also taking vitamin D3 daily and are concerned about the application method and possible shedding.

community M19 shed after 1yr on dutasteride

in Finasteride/Dutasteride 23 upvotes 1 year ago

A 19-year-old male experienced hair shedding after one year on dutasteride and is considering adding topical minoxidil despite scalp itching. Users suggest continuing dutasteride, maintaining a consistent hair routine, and possibly increasing minoxidil dosage.

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