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Research
5 / 1000+ resultsresearch Exogenous Alpha-Ketoglutaric Acid Alleviates the Rabbit Dermal Papilla Cell Oxidative Damage Caused by Hydrogen Peroxide Through the ERK/Nrf2 Signaling Pathway
This study found that α-ketoglutarate protected dermal papilla cells from oxidative stress by enhancing the Nrf2 pathway and mitigating cell damage through the ERK/Nrf2 axis.
research Stimulation of Hair Growth by Small Molecules that Activate Autophagy
This study found that activating autophagy with specific small molecules and drugs can stimulate hair growth by initiating the anagen phase in dormant hair follicles, suggesting a potential treatment for hair loss.
research Causal effects of genetically determined metabolites on androgenetic alopecia: A two‐sample Mendelian randomization analysis
This study used Mendelian randomization analysis to identify Scyllo-inositol and Alpha-ketoglutarate as potential protective factors and Heme and 2-palmitoylglycerophosphocholine as risk factors for androgenic alopecia, suggesting a causal link between these metabolites and the condition.
research Evaluating the Causal Relationship Between Human Blood Metabolites and the Susceptibility to Alopecia Areata
This study established a causal link between plasma metabolism and alopecia areata, providing insights into the disorder's mechanisms and suggesting directions for future screening and prevention strategies.
research Hair regeneration by small molecules that activate autophagy
This study reported that small molecules such as α-ketoglutarate, α-ketobutyrate, rapamycin, and metformin may stimulate hair regeneration by activating autophagy pathways.
Community Join
5 / 1000+ resultscommunity What can I use to prepare a lotion that doesn't irritate my scalp or make my hair sticky? (Want to experiment with metformin and Alpha Keto glutarate)
The conversation is about a user who tried dissolving a metformin pill in water for hair treatment but faced issues with hair sticking together. The user is seeking advice on preparing a non-irritating, non-sticky lotion at home, possibly experimenting with metformin and Alpha Keto glutarate.
community Bruteforcing alopecia or the new advent of science progress
Combining therapies like scyllo-inositol, alpha-ketoglutarate, and autophagy-inducing supplements may enhance hair growth and prevent hair loss. Reporting individual results can accelerate progress in hair loss treatments.
community 17-alpha-estradiol/Alfatradiol how does it Work for Hair loss?
17-alpha-estradiol may work for hair loss by inhibiting 5-alpha reductase, similar to finasteride. It might lower testosterone in the scalp, reducing DHT conversion.
community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?
Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.
community Mechanism of action of alfatradiol (17 alpha estradiol)
The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.
Clinics
6 / 29 results- 74
Hair TransplantHair Loss TreatmentsAlpha Beauty: Haartransplantation in HannoverHannover, Niedersachsen · DE - 25
Hair TransplantHair Loss TreatmentsSMPAlpha HaarkliniekAmsterdam · NL - 73
Hair TransplantAlpha Hair RestorationWinter Park, FL · US - 34
Hair TransplantHair Loss TreatmentsAlpha Keratix hair transplant & facial surgery clinicNagpur, Maharashtra · IN - 55
Hair TransplantHair Loss TreatmentsSMPAlpha Male Cosmetic CenterHouston, TX · US - 27SMPAlpha Micropigmentation LLCWest Jordan · US
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