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Did you mean Alopecia Totalis?

Glossary Alopecia Totalis

complete scalp hair loss due to autoimmune disorder

Alopecia Totalis (AT) is an advanced form of alopecia areata characterized by the complete loss of hair on the scalp. Unlike alopecia areata, which typically presents as patchy hair loss, AT results in total baldness of the head. This condition is believed to be an autoimmune disorder, where the body's immune system mistakenly attacks hair follicles, leading to hair loss.

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Research

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research Upadacitinib for the Management of Alopecia Totalis and Subtotalis in Pediatric Patients: A Case Series

February 2026 in “Reports — Medical Cases Images and Videos”

This retrospective case series reported that pediatric patients with alopecia totalis and subtotalis experienced significant hair regrowth after treatment with the JAK inhibitor upadacitinib, with mild acne as the most common side effect; however, larger studies are needed to establish its efficacy and safety conclusively.

research SDRIFE Induced by Tofacitinib

3 citations , May 2024 in “Indian Journal of Dermatology”

In this case report, researchers identified a potential adverse skin reaction, called SDRIFE or Baboon syndrome, caused by the drug tofacitinib in a 19-year-old woman being treated for alopecia subtotalis, leading the authors to recommend discontinuation of the drug.

research Trachyonychia secondary to pediatric alopecia areata responding to oral tofacitinib therapy: a case report and review of literature

January 2025 in “International Journal of Dermatology”

In this case report, a 14-year-old male with alopecia areata subtotalis and nail involvement showed significant improvement after 9 months of treatment with oral tofacitinib, including complete hair regrowth and nail texture improvement, though further studies are needed to confirm these findings.

research Assessment of prognostic markers of alopecia areata in pediatric patients

June 2023 in “International Journal of Research in Dermatology”

This study observed a high prevalence of severe markers among pediatric alopecia areata patients, identifying AA subtotalis as more frequent, with nail changes and various hair markers suggesting progression to severe forms.

research Topical Treatment of Extended Alopecia

17 citations , October 2009 in “Dermatology”

This study reported that ultraviolet light treatment from a Kromayer lamp stimulated hair growth in four out of six patients with alopecia, whereas intralesional triamcinolone acetonide had a mixed effect.

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Clinics

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Community Join

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community Alopecia Areata Question

2 upvotes 5 years ago

A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

community 29M alopecia or normal hair fall but something worked. Just wanted to share.

4 upvotes 1 year ago

A 29-year-old male experienced hair loss and found improvement using a combination of onion hair oil, castor oil, ketoconazole shampoo, and aloe vera gel with vitamin E, while discontinuing minoxidil and finasteride due to side effects. He emphasizes the importance of scalp massage and oiling for hair growth and reduced hair fall.

community Bruteforcing alopecia or the new advent of science progress

22 upvotes 1 year ago

Combining therapies like scyllo-inositol, alpha-ketoglutarate, and autophagy-inducing supplements may enhance hair growth and prevent hair loss. Reporting individual results can accelerate progress in hair loss treatments.

community The Real Cause Of Androgenetic Alopecia

675 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Fibrosing alopecia in a pattern distribution

in Research/Science 14 upvotes 2 years ago

A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

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Learn

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learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn GHK-Cu

Heard alopecia areata leaves scar-like spots? Some peptides are helping those areas regrow hair. Alopecia areata patches usually still have living follicles. Peptides are being studied as a possible add-on, but the evidence is small and early. See a dermatologist for treatment.

learn Salicylic acid

What makes alopecia areata different from other types of hair loss, and can topical Salicylic acid treatments help regrow the affected areas? Alopecia areata is an autoimmune condition, and salicylic acid does not promote hair regrowth.

learn Finasteride

Does hair strand thickness decrease in men with androgenic alopecia? Can finasteride help restore it? Androgenic alopecia thins hair strands by miniaturizing follicles. The pivotal finasteride trials (1,553 men, 1 mg/day, two years) report increased hair counts and improved assessed appearance, but they measured density, not the diameter of individual strands, so the effect on thickness itself is not established.
Finasteride for alopecia: the definitive guide to using it correctly. Finasteride 1 mg daily blocks DHT and, in trials, slowed hair loss in most men over 6 to 12 months, though some men do not respond and the benefit lasts only while the drug is taken. It is prescription-only and carries a pregnancy contraindication.

learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.

learn Hair Transplant

Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.

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