research Effect of Allopregnanolone and Allotetrahydrodeoxycorticosterone on Spike-Wave Discharges in the EEG of Absence Epilepsy Rat Models
The steroids allopregnanolone and allotetrahydrodeoxycorticosteron worsened absence seizures in rats.
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5 / 24 results research Isolation Rearing-Induced Reduction of Brain 5α-Reductase Expression: Relevance to Dopaminergic Impairments
Isolation stress in rats reduces brain enzyme levels, affecting dopamine function.
research 11β-Hydroxylase Inhibitors Protect Against Seizures in Mice by Increasing Endogenous Neurosteroid Synthesis
11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.
research Stress-Induced Deoxycorticosterone-Derived Neurosteroids Modulate GABA A Receptor Function and Seizure Susceptibility
Stress increases neurosteroids that help prevent seizures.
research Role of Anticonvulsant and Antiepileptogenic Neurosteroids in the Pathophysiology and Treatment of Epilepsy
Neurosteroids show promise for treating epilepsy and more research is needed.
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