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Highly Efficient Nucleophilic Addition of Alkyl Grignard Reagents to 17-Ketosteroids in the Presence of Cerium(III) Chloride: Synthesis of 17α-Propyl-17β-Hydroxy-4-Androsten-3-One, an Androgen Receptor Antagonist

research Highly Efficient Nucleophilic Addition of Alkyl Grignard Reagents to 17-Ketosteroids in the Presence of Cerium(III) Chloride: Synthesis of 17α-Propyl-17β-Hydroxy-4-Androsten-3-One, an Androgen Receptor Antagonist

14 citations, February 1994 in “Tetrahedron Letters”

Adding cerium(III) chloride to Grignard reagents improves the making of compounds that could treat prostate issues and hair loss.

Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase

research Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase

5 citations, February 1997 in “Bioorganic & Medicinal Chemistry”

New compounds were made that effectively block a specific enzyme related to androgen conditions.

research Effects of Ultraviolet B Radiation on Physicochemical Properties of Human Hair Shaft

5 citations, March 2012 in “Microscopy Research and Technique”

UVB radiation changes the chemical makeup and dries out human hair but doesn't alter its appearance or texture.

Synthesis and Biological Evaluation of Amino-Pyridines as Androgen Receptor Antagonists for Stimulating Hair Growth and Reducing Sebum Production

research Synthesis and Biological Evaluation of Amino-Pyridines as Androgen Receptor Antagonists for Stimulating Hair Growth and Reducing Sebum Production

17 citations, August 2007 in “Bioorganic & Medicinal Chemistry Letters”

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

research Core-Shell Nanocarriers Based on PEGylated Hydrophobic Hyperbranched Polyesters

7 citations, May 2016 in “European Polymer Journal”

The new nanocarriers improve how well water-insoluble drugs dissolve and allow for controlled drug release.

View more "alkyl chains" in research →

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community NW5 - 3 Month Results on Dermaroller + Minoxidil + Amplexe (COPPER TRIPEPTIDE-1 Shampoo)

in Treatment 13 upvotes 4 years ago

A user shared their positive 3-month results using a treatment for hair loss that includes Dermaroller, Minoxidil, and Amplexe Shampoo. They avoided using finasteride due to its risks.

community Methods Of Staying Safe On Ru58841 - My 2 Cents

in Research/Science 9 upvotes 2 weeks ago

RU58841 is used topically to prevent hair loss by blocking DHT, with suggestions to drink grapefruit juice, take breaks, avoid microneedling, and use lower concentrations to reduce side effects. Users discuss applying it at night to minimize systemic absorption.

community Finasteride and Oral Minoxidil in Turkey - what I’ve found out

in Finasteride/Dutasteride 10 upvotes 5 months ago

Finasteride is available in Turkey without a prescription, with 1mg tablets costing 800 Turkish lira and 5mg tablets costing 150 lira. Oral minoxidil capsules were found at Cerrahpaşa nur eczanesi, also without a prescription.