![Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase](/images/assets/d19df8a7-8de6-4430-8a0d-4ffa1f502985/small/15608.jpg)
5 citations
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February 1997 in “Bioorganic & Medicinal Chemistry” This study found that among 17 beta-(N-ureylene-N,N'-disubstituted)-4-azasteroids, those with an N'-phenyl moiety were the most effective inhibitors of human type I 5 alpha-reductase.
January 2011 in “Journal of Society of Cosmetic Chemists of Japan” This study found that a conditioner containing 18-MEA and SPDA can improve hair's smoothness and reduce flyaways, enhancing hair manageability.
July 2007 in “International Journal of Cosmetic Science” This study found that a new hybrid polymer made from hydrolyzed protein, alkyl chain, and silicone helped prevent discoloration and improve moisture feel and manageability in dyed and damaged hair.
January 2006 in “Journal of Society of Cosmetic Chemists of Japan” This study found that a new hybrid polymer containing hydrolyzed protein and silicone effectively improved moisture feel and prevented discoloration in dyed hair, particularly benefiting damaged hair.
2 citations
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January 2022 in “Materials today: proceedings” This study suggests that caffeine may enhance hair growth and be beneficial for cosmetic applications due to its high binding affinity to keratin, but further validation is needed.