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This study examined finasteride degradation under stress conditions, identifying three unique degradation products in acidic environments, providing insights into impurity profiling and quality control for finasteride formulations.

This study describes Hg(OTf)2 as a new and efficient catalyst for various organic synthesis reactions, including alkyne hydration and C–C bond forming cyclizations.

This study reports that difluoromethyl nitrile oxide can rapidly functionalize various alkenes at room temperature, leading to products that can transform into valuable medicinal chemistry building blocks like CF2H-isoxazolines for bioactive molecule modification.

In this study, researchers examined juglone's potential as a restoring agent for hair keratin damaged by permanent or bleaching treatments, finding that juglone formed Michael adducts with cysteine residues, leading to a more regular hair surface as observed via IR spectroscopy and SEM analysis.

In this study, novel substituted benzoyl benzoic acids and phenylacetic acids were potent and selective inhibitors of human steroid 5alpha-reductase type 2, with one compound showing promising bioavailability in rats for potential clinical evaluation.