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research The Effect of Alfacalcidiol and Metformin on Phenotype Manifestations in Women with Polycystic Ovary Syndrome – a Preliminary Study

14 citations , October 2016 in “Physiological Research”

In this study, vitamin D supplementation showed no significant effect on androgen levels or clinical hyperandrogenism in PCOS women, but when combined with metformin, it improved testosterone levels.

research The effect of alfacalcidiol and metformin on metabolic disturbances in women with polycystic ovary syndrome

10 citations , February 2017 in “Hormone Molecular Biology and Clinical Investigation”

This randomized clinical trial found that vitamin D supplementation did not significantly alter anthropometric or metabolic parameters in obese, insulin-resistant, and vitamin D-deficient women with polycystic ovary syndrome, whereas metformin effectively reduced body weight, BMI, waist circumference, total body fat, and serum glucose levels.

Alfatradiol (0.025%) - An Effective and Safe Treatment Option for Androgenetic Alopecia in Women and Men

research Alfatradiol (0,025 %) - Eine wirksame und sichere Therapieoption zur Behandlung der androgenetischen Alopezie bei Frauen und Männern

10 citations , December 2005 in “Aktuelle Dermatologie”

This study reported that after 7.5 months of treatment, topical Alfatradiol significantly increased anagen hair rates in women and men with androgenetic alopecia, with minimal side effects.

Daily Intake of Alfalfa Sprouts, But Not Broccoli Sprouts, Influences Plasma Levels of Androgen in Middle-Aged Males

research Daily intake of alfalfa sprouts, but not broccoli sprouts, influence plasma levels of androgen in middle-aged males

January 2018 in “Journal of translational science”

In this study, oral broccoli sprouts intake did not affect plasma androgen levels in males, while alfalfa sprouts intake increased testosterone and DHT levels, which may help prevent male late onset hypogonadism.

research Alfatradiol/minoxidil/trichofoam

March 2023 in “Reactions Weekly”

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Community Join

5 / 263 results

community Alfatradiol causing shedding ?

1 upvotes 1 year ago

The user experienced a sudden decrease in hair density after starting alfatradiol while already using finasteride. Another user mentioned that initial shedding can occur with hair loss treatments, but it may not last long.

community Alfatradiol 0.1% anyone know a source?

in Treatment 3 upvotes 1 year ago

The conversation is about finding a source for Alfatradiol 0.1% as most available products are 0.025%. A suggestion was made to use four times the dosage of the 0.025% product.

community Why is no one talking about alfatradiol?

22 upvotes 1 year ago

Alfatradiol is discussed as a hair loss treatment with minimal side effects, but its effectiveness is debated, and it's not widely known or available outside Germany. Some users report side effects like gyno and ball ache, while others find it effective in stopping shedding and itching.

community Alfatradiol anyone? Anyone added it to their regimen and found it helps?

4 upvotes 4 years ago

Alfatradiol helps reduce hair shedding and itching, and is effective for mild hair loss. Users combine it with treatments like fluridil, minoxidil, and sometimes consider finasteride.

community Does anyone use alfatradiol? Does it do anything at all??

6 upvotes 4 months ago

Alfatradiol is considered a mild treatment for hair loss, often used alongside other treatments like finasteride, minoxidil, and dutasteride. Users report it helps maintain hair but is not effective for regrowth on its own.

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Learn

1 / 801 results

learn Alfatradiol

a synthetic estrogen used topically as an anti-androgen

Alfatradiol: What does a form of estrogen have to do with hair loss in men? Alfatradiol (17α-estradiol) is a prescription topical hormone, licensed for androgenetic alopecia in Germany but not FDA-approved. The controlled trial evidence is in women, where it produced stabilisation rather than regrowth and was outperformed by minoxidil; no comparable placebo-controlled trial in men appears to have been published.
Does Alfatradiol work the same for women, men, and trans people? Almost all controlled data on topical alfatradiol comes from cisgender women, where it slowed hair loss rather than regrowing hair and was outperformed by minoxidil. No published controlled trial covers cisgender men, and none covers trans people at all — so the honest answer is that the difference has not been measured.
Alfatradiol: Is it safe to use if I’m already on finasteride or minoxidil? No published study has tested alfatradiol together with finasteride or minoxidil, so there is no direct evidence either way — no reported interaction, but also nothing that looked for one. Community members commonly combine them without reporting problems; ask a prescriber before adding a second agent aimed at the same DHT pathway.
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Clinics

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Experts

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