research Crosstalk Between Endothelial Cells and Dermal Papilla Entails Hair Regeneration and Angiogenesis During Aging
Communication between blood vessel and hair follicle cells decreases with age, affecting hair growth and blood vessel formation.
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research Distribution of Glycolipid and Unsaturated Fatty Acids in Human Hair
Human hair has more unsaturated fats inside than on the surface, and certain lipids may help bind the outer and inner layers together.
research Mechanistic Insights Into 5-Aminolevulinic Acid Photodynamic Therapy for Acne Vulgaris: Targeting Lipogenesis via the OLR1-Wnt/β-Catenin Pathway
This study explores the molecular mechanisms of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in treating acne vulgaris, focusing on its effects on lipid metabolism. Using an acne-like mouse model and human sebocytes, researchers found that ALA-PDT reduces lipogenesis by upregulating OLR1, which suppresses the SREBP1-FAS axis, leading to decreased lipid accumulation. The activation of the OLR1-Wnt/β-catenin pathway was crucial for these effects, as disrupting this pathway reversed the inhibition of lipogenesis. These findings suggest that targeting OLR1 could be a promising strategy for acne treatment.
research Untargeted Metabolomic Approach to Study the Serum Metabolites in Women with Polycystic Ovary Syndrome
Certain metabolites may help diagnose and predict polycystic ovary syndrome.
research Pathophysiology and Nutritional Approaches in Polycystic Ovary Syndrome: A Comprehensive Review
Eating a Mediterranean diet and taking certain supplements may improve symptoms of PCOS.
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5 / 24 resultscommunity How to BECOME a RESPONDER to Fin/Dut if you are not responding
The conclusion of this conversation is that the user "DuckSeasonCamelSeasn" found that consuming grapefruit juice prior to taking finasteride or dutasteride helped them become a responder to the medications and regain hair growth. However, there are warnings about potential risks and interactions with other medications, so caution should be exercised.
community M32 Finasteride (Saw palmetto before), minoxidil, nizoral, dermaroller
by
Karel_NOVAK2
in Journals / Progress Pictures
430 upvotes
9 months ago The user replaced finasteride with saw palmetto due to availability issues and experienced side effects, leading to adjustments in their regimen. They use saw palmetto, minoxidil, Nizoral, and a dermaroller, reporting reduced side effects and some benefits, with hair fall ranging from 5 to 20 hairs daily.
community Did Dutasteride change how you look physically? your facial profile such as skin thickness, fat distribution or softness?
Dutasteride and finasteride can cause changes in physical appearance, like more feminine features and increased water retention. Users report side effects such as reduced libido, weight gain, and improved skin clarity, while some notice no significant changes.
community Do we have to be junkies? That's funny
The conversation discusses using finasteride, dutasteride, minoxidil, cialis, and metformin to protect hair and health. Some users caution against self-prescribing these drugs due to potential risks and complications.
community After 11 Years On Finasteride, Unfortunately, Hair Is Starting To Thin Again. Does Hair Simply Get More Sensitive To DHT As You Age?
After 11 years on Finasteride, a user's hair is thinning again, suggesting hair may become more sensitive to DHT with age. They plan to introduce Dutasteride once a week, as they cannot tolerate Minoxidil.