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research Chemistry42: An AI-Driven Platform for Molecular Design and Optimization

180 citations , February 2023 in “Journal of Chemical Information and Modeling”

In this paper, Chemistry42—a software integrating AI with computational and medicinal chemistry—demonstrated efficiency in designing novel molecular structures targeting DDR1 and CDK20, with properties validated in both in vitro and in vivo studies.

research Modern Polycystic Ovary Syndrome (PCOS) Management: Intelligent Drug Delivery and Metabolic Reprogramming for Ovarian Restoration and Fertility Optimization

April 2026 in “Biomolecules”

This review highlights recent advancements in molecular understanding and treatment approaches for PCOS, including innovative drug delivery systems and AI-driven precision medicine, but provides no new clinical results.

research Hydrogel-based neural engineering for skin wound healing

1 citations , May 2026 in “Frontiers in Cell and Developmental Biology”

This review explores the potential of neuro-driven hydrogels for skin and nerve regeneration, integrating biochemical cues and advanced technologies like AI for personalized wound healing, but notes the need for further validation and trials before clinical use.

research Psychological Stress and Sleep Disturbance as Emerging Determinants of Hair Health: Mechanisms, Premature Greying, Hair Loss, and Preventive Strategies

August 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

This paper proposes an integrated model suggesting that psychological stress, sleep disturbances, nutrition, lifestyle, and various biological factors collectively influence hair health, including hair loss and premature greying.

research Psychological Stress and Sleep Disturbance as Emerging Determinants of Hair Health: Mechanisms, Premature Greying, Hair Loss, and Preventive Strategies

August 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

This study synthesizes evidence on the complex interplay between stress, sleep, nutrition, lifestyle, and systemic health and their impact on hair health, encompassing premature greying, hair loss, and follicle cycling.

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Community Join

5 / 595 results

community We should actually be hopeful for these recent new developments

112 upvotes 1 year ago

AI advancements, like AlphaFold, are speeding up drug discovery for hair loss, promising more effective treatments. Current options like minoxidil and finasteride have limitations, but new developments could improve solutions in 5-10 years.

community AH-001 another topical AR degrader beside GT20029, completed Phase I

8 upvotes 10 months ago

AH-001 is a new topical treatment designed to degrade androgen receptors, targeting the root cause of androgenetic alopecia without the side effects of oral treatments like finasteride. It has shown a strong safety profile and good local tolerability in early trials.

community 25 years on Finasteride and it's not working anymore.

324 upvotes 6 months ago

A 47-year-old has been using finasteride for 25 years for hair loss, but it's less effective now. Suggestions include switching to dutasteride, stopping anastrozole, and trying minoxidil, microneedling, and possibly TRT.

community Should I start Fin with these blood tests?

18 upvotes 3 years ago

A 25-year-old male with normal hormone levels is considering starting finasteride and minoxidil for hair loss but is concerned about high estradiol levels and potential side effects. Responses vary, with some suggesting blood tests before starting treatment and others emphasizing individual tolerance and the importance of consulting a doctor.

community Been on Dut since 2022, new doctor has concerns.

15 upvotes 4 months ago

A 31-year-old man has been using Dutasteride since 2022, alongside topical Minoxidil, with positive results and no issues. His new healthcare provider expressed concerns about long-term Dutasteride use and suggested alternatives like oral Minoxidil and Spironolactone, but the patient is hesitant to change a successful routine.

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