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This study found that Staphylococcus aureus delays wound healing by utilizing quorum sensing to impair lipid metabolism in keratinocytes, an effect not observed with commensal Staphylococcus, highlighting the impact of agr-dependent virulence factors in this process.

In this study, the authors observed that Staphylococcus aureus lipase gehB is crucial for bacterial penetration of hair follicles in mice, implicating lipases in inflammation and skin damage.

This study found that host androgens like testosterone promote Staphylococcus aureus pathogenesis and skin infections by activating the agr quorum sensing system, revealing a mechanism for sex-dependent differences in these infections.

The researchers reported that carnosic acid and carnosol, extracts from rosemary leaves, specifically inhibit S. aureus virulence expression, suggesting potential topical treatments for atopic dermatitis flares.

This study suggests that sodium-glucose cotransporter-2 inhibitors, alone or with metformin or GLP1RA, may improve metabolic and hormonal parameters in women with polycystic ovary syndrome.