This study found that both genetic and epigenetic factors significantly influence age-related facialskinaging, with lifestyle and environmental factors also playing a substantial role.
36 citations
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October 2015 in “Journal of Cosmetic Dermatology”
In this study, a new apple stem cell extract serum significantly improved signs of skinaging and enhanced cell metabolism in human senescent fibroblasts, showing visible effects after one week of use.
December 2025 in “Clinical Cosmetic and Investigational Dermatology”
This study highlights the potential of ZDHHC17 methylation as a biomarker or therapeutic target in addressing skinaging, offering new insights into its molecular mechanisms.
120 citations
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July 2005 in “Dermatologic surgery”
This study found that topical niacinamide significantly improved the appearance of wrinkles, skin yellowing, and elasticity in agingfacialskin over 12 weeks.
A user reported significant facialaging after using minoxidil for hair loss, despite a good skincare routine and healthy lifestyle. They plan to switch to dutasteride and possibly stop minoxidil.
Oral minoxidil may cause facial puffiness or aging in some users, but results vary. Many users experience positive hair growth and stress the importance of skincare and a healthy lifestyle.
Dutasteride and finasteride can cause changes in physical appearance, like more feminine features and increased water retention. Users report side effects such as reduced libido, weight gain, and improved skin clarity, while some notice no significant changes.
A 34-year-old male, already on finasteride, is hesitant to continue minoxidil due to side effects like headaches and concerns about facial bloating and skinaging. Another user shares their experience with minoxidil causing facial bloating but hopes for hair growth benefits.
Minoxidil may cause facialaging, possibly due to alcohol and propylene glycol (PG) content. The user plans to reduce Minoxidil and Finasteride to one daily dose to minimize these effects.