87 citations
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March 2013 in “Expert Review of Anticancer Therapy” Afatinib often causes skin problems that need proactive management.
December 2022 in “International Journal of Molecular Sciences” Afatinib, neratinib, and zanubrutinib could be effective against KRASG12C-mutant tumors.
58 citations
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March 2020 in “Scientific Reports” EGFR-TKIs can cause significant skin, nail, and organ side effects.
7 citations
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January 2023 in “Anti-Cancer Drugs” Early diagnosis and treatment of EGFR inhibitor-induced folliculitis decalvans can prevent permanent hair loss.
June 2024 in “Journal of Clinical Oncology” EGFR-TKIs can cause unexpected skin, nail, and hair issues.