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research Factors affecting bone maturation in Chinese girls aged 4-8 years with isolated premature thelarche

July 2020 in “Research Square (Research Square)”

In this study, researchers found that girls aged 4-8 years with isolated premature thelarche had significantly advanced bone age, with obesity and elevated serum IGF-1 SDS and DHEAS SDS being key independent risk factors.

research Factors affecting bone maturation in Chinese girls aged 4-8 years with isolated premature thelarche

July 2020 in “Research Square (Research Square)”

This study found that girls with isolated premature thelarche, confirmed by GnRH stimulation test, aged 4-8 years, may have significantly advanced bone age, with obesity and serum IGF-1 and DHEAS levels being key risk factors.

An Update on Congenital Adrenal Hyperplasia

research An Update of Congenital Adrenal Hyperplasia

151 citations , December 2004 in “Annals of the New York Academy of Sciences”

This review discusses nonclassical 21-hydroxylase deficiency as the most common autosomal recessive disorder in humans and highlights the effectiveness of glucocorticoid treatment in reversing related symptoms.

research Central Precocious Puberty and Sjogren-Larsson Syndrome in a Child: A Rare Case Report

July 2026 in “Clinical Cosmetic and Investigational Dermatology”

In this case report, a 9-year-old boy with Sjogren-Larsson syndrome was also diagnosed with central precocious puberty, showing genetic mutations and increased hormone levels; he was treated with triptorelin acetate for CPP but experienced growth delay during follow-up.

research Evaluation of Premature Pubarche Cases: A Single CenterExperience

April 2017

This study found that 20% of children initially diagnosed with premature pubarche were later identified with different clinical conditions during follow-up, highlighting the need for careful differential diagnosis over time.

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community If we can clone a sheep why we can't cure baldness till now

in Research/Science 181 upvotes 1 year ago

Hair loss treatments like Minoxidil, finasteride, and stem cell therapies exist, but a complete cure is hindered by genetic complexity and market dynamics. Cloning hair follicles is considered a potential solution, but it's currently not feasible.

community 3 surgery total 7600 Grafts surgery journey

726 upvotes 7 months ago

A person had three hair transplant surgeries using 7,600 grafts from scalp, beard, and chest, along with finasteride and minoxidil. Reactions are mixed, with suggestions for alternatives like hair systems or scalp micropigmentation.

community Dht kills hair, but no one says why?

in Finasteride/Dutasteride 40 upvotes 1 year ago

DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

community Why not just take the drugs before hair loss?

in Chat 123 upvotes 6 months ago

Finasteride and dutasteride are discussed as preventative treatments for hair loss, with some advocating for early use and others concerned about side effects, especially before full maturity. Many regret not starting these treatments earlier due to their effectiveness in preventing or slowing hair loss.

community For those who regrew their hair: how did it change your dating life?

in Chat 13 upvotes 1 year ago

Regrowing hair with finasteride and minoxidil can boost confidence and improve dating prospects. However, confidence and personality are considered more important than appearance in relationships.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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