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GlossaryAdult Stem Cells

undifferentiated cells in adults that regenerate specific tissues

Adult stem cells, also known as somatic stem cells, are undifferentiated cells found throughout the body after development. They have the ability to self-renew and differentiate into various specialized cell types of the tissue or organ they reside in, playing a crucial role in tissue repair and regeneration. Unlike embryonic stem cells, adult stem cells are limited in their differentiation potential but are less likely to cause ethical concerns or immune rejection when used in therapies.

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research Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair

24 citations, May 2016 in “Stem Cell Reviews and Reports”

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

research Hair Follicle Stem Cells as a Skin-Organizing Signaling Center During Adult Homeostasis

25 citations, April 2021 in “The EMBO Journal”

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

research Signaling Couples Hair Follicle Stem Cell Quiescence With Reduced Histone H3 K4/K9/K27me3 for Proper Tissue Homeostasis

31 citations, April 2016 in “Nature communications”

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

research Hardwiring Stem Cell Communication Through Tissue Structure

82 citations, March 2016 in “Cell”

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

research A Matter of Life and Death: Self-Renewal in Stem Cells

150 citations, December 2012 in “EMBO Reports”

Stem cell self-renewal is complex and needs more research for full understanding.

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community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 1 year ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community Why is it that low testosterone causes hair loss as well? How can I be balding?

in Chat 158 upvotes 7 months ago

The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 2 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 667 upvotes 1 month ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

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