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GlossaryAdult Stem Cells

undifferentiated cells in adults that regenerate specific tissues

Adult stem cells, also known as somatic stem cells, are undifferentiated cells found throughout the body after development. They have the ability to self-renew and differentiate into various specialized cell types of the tissue or organ they reside in, playing a crucial role in tissue repair and regeneration. Unlike embryonic stem cells, adult stem cells are limited in their differentiation potential but are less likely to cause ethical concerns or immune rejection when used in therapies.

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research SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells

330 citations, December 2009 in “Cell stem cell”

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

research Skipping a Hurdle: Sox2 and Adult Dermal Stem Cells

11 citations, December 2009 in “Cell stem cell”

Sox2-expressing cells can help grow hair and heal skin.

research Diversity of Adult Stem Cell Niches in the Dermal Compartment of Skin

1 citations, January 2018 in “Elsevier eBooks”

The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.

research Platelet-Derived Growth Factor Signaling Modulates Adult Hair Follicle Dermal Stem Cell Maintenance and Self-Renewal

37 citations, April 2017 in “npj Regenerative Medicine”

PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.

research Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells

26 citations, February 2012 in “Journal of Investigative Dermatology”

Human hair follicle cells can be successfully transformed into different types of cells, but not more efficiently than other adult cells.

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community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 107 upvotes 2 months ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 668 upvotes 2 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community 18-year progress pics. Fin only.

in Progress Pictures 419 upvotes 2 months ago

The user has been using finasteride for 18 years to manage hair loss and is considering starting minoxidil and possibly a hair transplant. Despite some regrowth, they are exploring additional treatments like dutasteride and oral minoxidil due to continued hair thinning.

community Fats on your Head to Stop Hair Loss?

in Research/Science 140 upvotes 10 months ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community Please stop looking for a natural way to stop your hairloss

in Chat 247 upvotes 2 years ago

There is no natural way to stop hair loss; pharmaceuticals like minoxidil, finasteride, and RU58841 are the only effective treatments. Some users report success with minoxidil and microneedling, while others discuss the side effects of finasteride.

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