June 2025 in “Stem Cell Research & Therapy” In this study, researchers found that isoproterenol, an adrenergic β2 receptor agonist, promoted hair growth and hair follicle stem cell proliferation in models of androgenetic alopecia by modulating the PI3K/AKT/β-Catenin pathway, suggesting a potential new therapeutic strategy for hair loss.
8 citations
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January 2016 in “Cells tissues organs” This study found that chemical sympathectomy inhibited hair follicle growth in mice, suggesting that sympathetic nerves may regulate keratinocyte behavior to promote hair growth.
44 citations
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June 2017 in “The EMBO Journal” This study reports that the autotaxin–LPA–LPA3 signaling pathway at the embryo-epithelial boundary plays a critical role in decidualization by up-regulating HB-EGF and COX-2 in the uterine epithelium.
2 citations
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September 2022 in “Frontiers in veterinary science” In this study, researchers used high-throughput sequencing to explore lncRNA interactions in cashmere goat hair follicles during embryonic development, finding lncRNAs potentially regulate genes in the Wnt and PI3K-Akt pathways related to hair follicle growth.
2 citations
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August 2020 in “Scientific reports” This study identified genes potentially involved in the development and differentiation of skin appendages in Atelerix albiventris, noting significant enrichment of immune-related genes in hair-type tissues.