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research Structure and Expression of a New Complementary DNA Encoding the almost Exclusive 3β-Hydroxysteroid Dehydrogenase/Δ⁵-Δ⁴-lsomerase in Human Adrenals and Gonads

354 citations , August 1991 in “Molecular Endocrinology”

This study found that distinct isoenzymes of 3 beta-hydroxysteroid dehydrogenase are expressed in human adrenals and gonads compared to the placenta and skin.

An Update on Congenital Adrenal Hyperplasia

research An Update of Congenital Adrenal Hyperplasia

151 citations , December 2004 in “Annals of the New York Academy of Sciences”

This review discusses nonclassical 21-hydroxylase deficiency as the most common autosomal recessive disorder in humans and highlights the effectiveness of glucocorticoid treatment in reversing related symptoms.

research Neuroimmunoregulation of Androgens in the Adrenal Gland and the Skin

48 citations , January 2000 in “Hormone Research in Paediatrics”

This article reviews the regulation of androgens in human skin and adrenals, highlighting their role in skin disorders, but reports no new research findings.

Stimulating Effect of Adrenalectomy on Hair Growth and Melanin Deposition in Black Rats Fed Diets Adequate and Deficient in the Filtrate Factors of Vitamin B1

research STIMULATING EFFECT OF ADRENALECTOMY ON HAIR GROWTH AND MELANIN DEPOSITION IN BLACK RATS FED DIETS ADEQUATE AND DEFICIENT IN THE FILTRATE FACTORS OF VITAMIN B¹

34 citations , January 1943 in “Endocrinology”

In this study, adrenalectomy in rats on a diet lacking certain vitamin B components reversed fur graying and enhanced hair growth.

The Effects of Synthetic and Natural Hormones of the Adrenal Cortex on Melanin Deposition in Adrenalectomized Black Rats Fed Diets Adequate and Deficient in Vitamin B1

research THE EFFECTS OF THE SYNTHETIC AND NATURAL HORMONE OF THE ADRENAL CORTEX ON MELANIN DEPOSITION IN ADRENALECTOMIZED BLACK RATS FED DIETS ADEQUATE AND DEFICIENT IN THE FILTRATE FACTORS OF VITAMIN B¹

27 citations , October 1945 in “Endocrinology”

In this study, adrenalectomy in black rats on a vitamin B-deficient diet restored hair growth and melanin deposition, effects reversed using adrenal cortical hormones.

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community Dutasteride 2.5 mg Progress (6 months)

181 upvotes 5 months ago

A 49-year-old male switched from Finasteride to Dutasteride 2.5 mg daily, along with oral Minoxidil 5 mg, resulting in significant hair regrowth and stopping hair loss after six months. Despite initial side effects like adrenaline spikes and urinary issues, the user is satisfied with the results and plans to continue the treatment.

community Thoughts about ORAL ketoconazole? (pills)

8 months ago

Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.

community DHEA, the culprit behind DUPA ? Read this!

20 upvotes 3 years ago

High DHEA levels may contribute to hair loss by increasing DHT in hair follicles, potentially explaining why finasteride is ineffective for some. Treatments like high-dose dutasteride and RU58841 are suggested, but the underlying cause, such as adrenal issues, should be investigated.

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