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GlossaryAdipose-Derived Stem Cells

stem cells harvested from fat tissue for regenerative purposes

Adipose-Derived Stem Cells (ADSCs) are stem cells that are harvested from fat tissue. These cells have the ability to differentiate into various cell types, including bone, cartilage, and muscle cells, making them valuable for regenerative medicine and tissue engineering. They are also being researched for their potential in treating conditions like alopecia, as they can promote hair growth and repair damaged hair follicles.

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Systematic Review: Adipose-Derived Mesenchymal Stem Cells, Platelet-Rich Plasma, and Biomaterials as New Regenerative Strategies in Chronic Skin Wounds and Soft Tissue Defects

research Systematic Review: Adipose-Derived Mesenchymal Stem Cells, Platelet-Rich Plasma, and Biomaterials as New Regenerative Strategies in Chronic Skin Wounds and Soft Tissue Defects

70 citations, February 2021 in “International Journal of Molecular Sciences”

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

The Combined Use of Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells Promotes Healing: A Review of Experimental Models and Future Perspectives

research The Combined Use of Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells Promotes Healing: A Review of Experimental Models and Future Perspectives

4 citations, September 2021 in “Biomolecules”

Using Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells together can improve healing, including wound healing, bone regeneration, and hair growth.

research Hair Loss and Telogen Effluvium Related to COVID-19: The Potential Implication of Adipose-Derived Mesenchymal Stem Cells and Platelet-Rich Plasma as Regenerative Strategies

3 citations, August 2022 in “International Journal of Molecular Sciences”

COVID-19 can cause hair loss, and treatments like PRP and stem cells might help.

research Mir-574-3p and Mir-125a-5p in Adipose-Derived Mesenchymal Stem Cell Exosomes Synergistically Target TGF-β1/Smad2 Signaling Pathway for the Treatment of Androgenic Alopecia

April 2025 in “Journal of Investigative Dermatology”

Two microRNAs in stem cell exosomes help treat hair loss by targeting a specific signaling pathway.

research The Potential of Spirulina Maxima Extract-Treated Conditioned Medium From Adipose-Derived Mesenchymal Stem Cells for Hair Growth Promotion on Human Dermal Papilla Cells

March 2025 in “Regenerative Therapy”

Spirulina maxima extract may help hair growth by boosting cell activity.

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community Anyone Try Microneedling with Exosomes/AAPE?

in Microneedling 2 upvotes 3 years ago

User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 445 upvotes 4 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 9 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community New Hair Loss Treatment: Adipose Derived Secretomes

in Research/Science 18 upvotes 3 weeks ago

Adipose-derived stem cell secretome showed significant improvement in hair density and growth, especially when combined with minoxidil, suggesting a synergistic effect. The study had limitations, including a small sample size and potential bias.

community STEM CELL TREATMENT FOR HAIR LOSS at home

in Treatment 6 upvotes 4 years ago

User considers trying AAPE for hair restoration, costing $700 for 6 months. Others discuss its potential effectiveness and mention a study with promising results.

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