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GlossaryAdipose-Derived Stem Cells

stem cells harvested from fat tissue for regenerative purposes

Adipose-Derived Stem Cells (ADSCs) are stem cells that are harvested from fat tissue. These cells have the ability to differentiate into various cell types, including bone, cartilage, and muscle cells, making them valuable for regenerative medicine and tissue engineering. They are also being researched for their potential in treating conditions like alopecia, as they can promote hair growth and repair damaged hair follicles.

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Combined Therapy with Adipose Tissue-Derived Mesenchymal Stromal Cells and Meglumine Antimoniate Controls Lesion Development and Parasite Load in Murine Cutaneous Leishmaniasis Caused by Leishmania Amazonensis

research Combined Therapy with Adipose Tissue-Derived Mesenchymal Stromal Cells and Meglumine Antimoniate Controls Lesion Development and Parasite Load in Murine Cutaneous Leishmaniasis Caused by Leishmania Amazonensis

5 citations, August 2020 in “Stem Cell Research & Therapy”

Using fat-derived stem cells with the drug meglumine antimoniate can help control skin disease and reduce parasites in mice with leishmaniasis.

research Extracellular Vesicles from Hair Follicle-Derived Mesenchymal Stromal Cells: Isolation, Characterization, and Therapeutic Potential for Chronic Wound Healing

22 citations, April 2022 in “Stem cell research & therapy”

Hair follicle-derived extracellular vesicles may help heal chronic wounds as effectively as those from adipose tissue.

research Soy Protein/Beta-Chitin Sponge-Like Scaffolds Laden With Human Mesenchymal Stromal Cells Promote Diabetic Chronic Wound Healing

1 citations, December 2023 in “Biomaterials advances”

Sponges made of soy protein and β-chitin with human cells from hair or fat can speed up healing of chronic wounds.

research Mesenchymal Stem Cells and Stromal Vascular Fraction for Hair Loss

13 citations, August 2018 in “Facial Plastic Surgery Clinics of North America”

Adipose tissue shows promise for hair regrowth, but more research is needed to confirm best practices and effectiveness.

research Human Hair Follicle-Derived Mesenchymal Stromal Cells from the Lower Dermal Sheath as a Competitive Alternative for Immunomodulation

7 citations, January 2022 in “Biomedicines”

Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community My opinions on hair treatment right now and in future

in Treatment 22 upvotes 4 years ago

Finasteride, minoxidil, dermarolling, and topical antiandrogens are effective for hair regrowth. Future treatments may include CB0301 and hair cloning.

community Increased adipose tissue (being overweight) in males may increase likelyhood of finasterde side effects

in Research/Science 29 upvotes 2 months ago

Being overweight may increase finasteride side effects due to higher aromatase activity converting testosterone to estradiol. Maintaining a healthy weight could reduce these side effects.

community The Big Fat Layer II

in Research/Science 26 upvotes 3 years ago

Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

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