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Intraoperative Bioprinting of Human Adipose-Derived Stem Cells and Extracellular Matrix Induces Hair Follicle-Like Downgrowths and Adipose Tissue Formation During Full-Thickness Craniomaxillofacial Skin Reconstruction

research Intraoperative Bioprinting of Human Adipose-Derived Stem Cells and Extracellular Matrix Induces Hair Follicle-Like Downgrowths and Adipose Tissue Formation During Full-Thickness Craniomaxillofacial Skin Reconstruction

1 citations, October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.

Human Adipose Tissue-Derived Small Extracellular Vesicles Promote Soft Tissue Repair Through Modulating M1-To-M2 Polarization Of Macrophages

research Human Adipose Tissue-Derived Small Extracellular Vesicles Promote Soft Tissue Repair Through Modulating M1-To-M2 Polarization Of Macrophages

2 citations, April 2023 in “Stem Cell Research & Therapy”

Tiny fat-derived particles can help repair soft tissues by changing immune cell types.

research Comparison of the Therapeutic Effect of Allogeneic and Xenogeneic Small Extracellular Vesicles in Soft Tissue Repair

18 citations, September 2020 in “International Journal of Nanomedicine”

Both human and animal-derived small extracellular vesicles speed up skin healing equally well.

research The Efficacy of Adipose-Derived Stem Cells in Burn Injuries: A Systematic Review

1 citations, January 2024 in “Cellular & Molecular Biology Letters”

Adipose-derived stem cells help heal burns but need more research.

research The Angiogenic Potential of Mesenchymal Stem Cells from the Hair Follicle Outer Root Sheath

8 citations, February 2021 in “Journal of Clinical Medicine”

Hair follicle stem cells are promising for blood vessel formation and tissue repair.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community Increased adipose tissue (being overweight) in males may increase likelyhood of finasterde side effects

in Research/Science 29 upvotes 2 months ago

Being overweight may increase finasteride side effects due to higher aromatase activity converting testosterone to estradiol. Maintaining a healthy weight could reduce these side effects.

community Topical finasteride now the safest possible path?

in Finasteride/Dutasteride 72 upvotes 4 months ago

Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

community Nice & pure PRP, 3 ml of this is going to the scalp.

in Research/Science 32 upvotes 2 years ago

The use of PRP to treat hair loss and its potential effectiveness when combined with 5 alpha reductase blockers such as Minoxidil or Finasteride.

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