December 2025 in “Scientific Reports” In this study, cedrol was found to reduce lipid accumulation in the liver and adipose tissues of dexamethasone-treated mice by antagonizing glucocorticoid receptors, suggesting its potential utility in treating dexamethasone-induced lipid metabolism disorders.
70 citations
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July 2016 in “Aging” This study suggests that dermal adipocytes might play a key role in skin aging due to their transformation into fibrotic structures in chronically photo-damaged skin.
41 citations
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September 2014 in “Journal of Pharmacy and Pharmacology” This study found that melatonin significantly improved metabolic and reproductive parameters in PCOS-induced rats, with effects similar to metformin.
January 2021 in “ISGE series” This article discusses PCOS, highlighting its association with insulin resistance and chronic inflammation, and suggests that nutrition, exercise, and supplements may improve body composition and metabolic function, but reports no new clinical results.
April 2019 in “Journal of Investigative Dermatology” This study found that mice lacking REDD1 experienced an expansion of dermal white adipose tissue through both hypertrophy and hyperplasia, suggesting a potential therapeutic target for skin adipogenesis regulation.