This study observed that follistatin and activin interactions significantly influence hair follicle development in mice, suggesting potential regenerative treatments for alopecia.
This study found that overexpression of activin in transgenicmice led to enhanced granulation tissue formation after skin injury due to changes in keratinocyte proliferation and differentiation.
81 citations
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January 2003 in “The FASEB Journal”
This study found that follistatin and activin interactions are important for hair follicle development and cycling in mice, suggesting that they may regulate processes involving BMP-2 and its antagonist.
113 citations
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December 2000 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”
This study reports that overexpression of activin in transgenicmice enhances granulation tissue formation during wound healing, highlighting a novel role for activin in cutaneous repair processes.