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This paper reviews the literature on acquired trichorrhexis nodosa, a clinical hair loss diagnosis associated with hair care practices, particularly in those with tightly curled hair, and emphasizes management through protective hair care regimens rather than traditional prescription therapies.

In this case series, mesenchymal stem cell exosomes were reported to improve hair length, density, pigmentation, and cuticle layer recovery in three patients with acquired trichorrhexis nodosa, suggesting potential as a therapeutic approach for this hair condition.

This case study reports that reducing scalp massage following minoxidil application and using mesenchymal stem cell exosomes led to significant improvement in hair condition for a patient with trichorrhexis nodosa.

This case study reported that a 15-year-old female developed acquired localized trichorrhexis nodosa, a hair shaft disorder, due to vigorous rubbing of an herbal powder on her scalp as part of local cultural practices.

This case study describes an acquired localized form of trichorrhexis nodosa resulting from physical-chemical trauma.