29 citations
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January 2016 in “Experimental Dermatology” This article discusses how mechanical stress may contribute to the development of hidradenitis suppurativa lesions, drawing on historical research and highlighting the possible role of IL-17-mediated inflammation.
62 citations
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July 2022 in “Science Immunology” This study discovered that TREM2 macrophages influenced by squalene play a role in acne's development by hindering the killing of Cutibacterium acnes, helping explain why benzoyl peroxide is effective in treatment.
18 citations
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October 2014 in “Experimental Dermatology” Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.
19 citations
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April 2019 in “Journal of the European Academy of Dermatology and Venereology” This study found that acne lesion formation involves early hyperkeratinization and inflammation around hair follicles, creating a self-sustaining cycle that may progressively worsen acne.
198 citations
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January 1998 in “Dermatology” This review discusses human sebocyte in vitro models for studying sebaceous gland function and control but reports no new clinical results, highlighting hormonal effects and the impact of retinoids on sebocyte activity.