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    GlossaryAcetylcholinesterase (AChE)

    breaks down acetylcholine in the synaptic cleft

    Acetylcholinesterase (AChE) is an enzyme that breaks down the neurotransmitter acetylcholine in the synaptic cleft, which is the space between nerve cells. This process is crucial for terminating nerve impulses and allowing muscles to relax after contraction. Inhibiting AChE can lead to prolonged muscle contraction and is a mechanism used by certain nerve agents and pesticides.

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      community Minoxidil results in 3 months after stopping fin

      in Is this regrowth?  469 upvotes 5 months ago
      The user stopped finasteride due to testicular aches and switched to minoxidil, seeing positive results in three months. They are considering topical finasteride but are cautious because of past side effects from oral use.

      community Gyno caused by finasteride?

      in General  75 upvotes 2 weeks ago
      The user is experiencing chest sensitivity and muscle ache after using topical finasteride for a month and is concerned about potential gynecomastia. They are considering asking their doctor for blood work to check estrogen levels and are questioning whether to stop using finasteride.

      community Pyrilutamide update number 2 - 2 week use

      in Update  174 upvotes 2 years ago
      An update on the use of Pyrilutamide, a new drug for hair loss, which has resulted in no shedding or testicle ache; other users have questioned the science behind this and shared their own experiences with Finasteride, Minoxidil, and microneedling.

      community Why is no one talking about alfatradiol?

      in Treatment  24 upvotes 7 months ago
      Alfatradiol is discussed as a hair loss treatment with minimal side effects, but its effectiveness is debated, and it's not widely known or available outside Germany. Some users report side effects like gyno and ball ache, while others find it effective in stopping shedding and itching.

      community 1.5 years dut oral min results

      in Finasteride/Dutasteride  512 upvotes 1 year ago
      The conversation discusses a user's 1.5-year experience with oral minoxidil and dutasteride for hair loss, mentioning side effects like itchy nipples and ball ache. Specific treatments used are 5mg of minoxidil and 0.5mg of dutasteride daily.